Nafcillin sodium salt monohydrate
7177-50-6 Basic informationMore
- Product Name:Nafcillin sodium salt monohydrate
- Synonyms: Nafcillin monohydrate sodium salt D00928 Nafcillin sodium (usp) Unipen (tn) Nafcillin sodium salt monohydrate,6-(2-Ethoxy-1-naphthamido)penicillin Nafcillin Sodium (200 mg) Nafcillin sodiuM salt Monohydr CL 8491
- CAS:7177-50-6
- MF:C21H25N2NaO6S
- MW:456.49
- EINECS:628-594-2
- Mol File:7177-50-6.mol
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USE
Nafcillin sodium, 6-(2-ethoxy-1-naphthyl)penicillin sodium(Unipen), is another semisynthetic penicillin that resultedfrom the search for penicillinase-resistant compounds. Likemethicillin, nafcillin has substituents in positions ortho tothe point of attachment of the aromatic ring to the carboxamidegroup of penicillin. No doubt, the ethoxy group andthe second ring of the naphthalene group play steric roles instabilizing nafcillin against penicillinase. Very similar structureshave been reported to produce similar results in somesubstituted 2-biphenylpenicillins. <br>Unlike methicillin, nafcillin is stable enough in acid topermit its use by oral administration. When it is givenorally, its absorption is somewhat slow and incomplete,but satisfactory plasma levels may be achieved in about1 hour. Relatively small amounts are excreted throughthe kidneys; most is excreted in the bile. Even thoughsome cyclic reabsorption from the gut may occur, nafcillingiven orally should be readministered every 4 to 6 hours.This salt is readily soluble in water and may be administeredintramuscularly or intravenously to obtain highplasma concentrations quickly for the treatment of seriousinfections.<br>Nafcillin sodium may be used in infections causedsolely by penicillin G-resistant staphylococci or whenstreptococci are present also. Although it is recommendedthat it be used exclusively for such resistant infections, nafcillin is also effective against pneumococci and groupA -hemolytic streptococci. Because, like other penicillins,it may cause allergic side effects, it should be administeredwith care.
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- Nafcillin sodium salt monohydrate
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- US $0.00 /Kg/Bag
- CAS:7177-50-6
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 20ton
- 2023-06-29
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- Company Name:CSPC Zhongnuo Pharmaceutical (Shijiazhuang) Co., Ltd.
- Tel:0311-83092265
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- CB Index:60
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- Company Name:Shandong Xiya Chemical Co., Ltd
- Tel:4009903999 13355009207
- Products Intro:CAS:7177-50-6
Purity:98% Package:25g;100g;500g;1kg - CB Index:57
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- Products Intro:Product Name:Nafcillin sodium salt monohydrate
CAS:7177-50-6
Purity:99% HPLC Package:10g;50g;100g;500g;1kg;5kg;25kg More... - CB Index:57
- Related Information:Catalog(11726)
- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-400-6206333 18521732826
- Products Intro:Product Name:Nafcillin sodium salt monohydrate
CAS:7177-50-6
Purity:98% Package:1g/RMB 298.90;5g/RMB 1029.90 More... - CB Index:65
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