Bortezomib
179324-69-7 Basic informationMore
- Product Name:Bortezomib
- Synonyms: Boronic acid, B-[(1R)-3-Methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)aMino]propyl]aMino]bu MG-341 PS-341 BortezoMib Base bortezoMib(other) MLM341 BortezoMib R VELCADE(BORTEZOMIB) Boronic acid, B-[(1R)-3-methyl-1-[[(2S)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]-
- CAS:179324-69-7
- MF:C19H25BN4O4
- MW:384.24
- EINECS:605-854-3
- Mol File:179324-69-7.mol
USE
Bortezomib belong to the class of drugs called proteasome inhibitors and is licensed in the United States and
the United Kingdom for the treatment of multiple myeloma. The drug has been licensed for patients in whom
the myeloma has progressed despite prior treatment or where a bone marrow transplant is not possible or was
not successful. It is marketed under the name Velcade? or Cytomib?. Velcade is administered via injection
and is sold as powder for reconstitution.<br/>
Bortezomib was the first drug approved in the new drug class of proteasome inhibitors and boron seems to
be its active element. For the mode of action, it is believed that the boron atom binds with high affinity and
specificity to the catalytic site of 26S proteasome and inhibits its action. Therapy with Bortezomib can lead
to a variety of adverse reactions, including peripheral neuropathy, myelosuppression, renal impairment and
gastrointestinal (GI) disturbances together with changes in taste. Nevertheless, the side effects are in most
cases less severe than with alternative treatment options such as bone marrow transplantation.
Lastest Price from Bortezomib manufacturers
- Bortezomib
- US $0.00 /kg
- CAS:179324-69-7
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 2000ton
- 2024-04-12
- Bortezomib
- US $0.00 /KG
- CAS:179324-69-7
- Min. Order: 100g
- Purity: 98%+
- Supply Ability: 100kg
- 2024-03-16
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- Company Name:Shandong Platinum Pharmaceutical Co., Ltd.
- Tel:0531-0531-69954981 88963280 15666777973
- Products Intro:Product Name:Bortezomib
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- Company Name:Jiangsu Vcare PharmaTech Co., Ltd.
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