Flucloxacillin
5250-39-5 Basic informationMore
- Product Name:Flucloxacillin
- Synonyms: (2S,5R,6R)-6-[[3-(2-chloro-6-fluoro-phenyl)-5-methyl-1,2-oxazol-4-yl]carbonylamino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid (2S,5R,6R)-6-[[3-(2-chloro-6-fluoro-phenyl)-5-methyl-isoxazole-4-carbonyl]amino]-7-keto-3,3-dimethyl-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid Fluchlxacillin Flopen Floxapen Flucil Flucloxcillin Staphylex
- CAS:5250-39-5
- MF:C19H17ClFN3O5S
- MW:453.87
- EINECS:226-051-0
- Mol File:5250-39-5.mol
-
USE
Oral absorption: c. 80%<br />
C<sub>max</sub> 250 mg (oral): 11 mg/L after 0.5–1 h<br />
Plasma half-life: 2 h<br />
Plasma protein binding: 95%<br />
<strong>Absorption and distribution</strong><br />
It is well absorbed after oral administration and penetrates rapidly into extravascular exudates. Its high protein binding limits its diffusion, notably into the normal CSF.<br />
<strong><strong>Metabolism and excretion</strong></strong><br />
Flucloxacillin is partly metabolized in the liver and about 10% of the plasma concentration is made up of metabolites. It is more slowly eliminated than cloxacillin. Some appears in the bile but about 50–80% of an oral dose is recovered from the urine, about 20% as metabolites.
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- Company Name:Shanghai Hanhong Scientific Co.,Ltd.
- Tel:021-54306202 13764082696
- Products Intro:Product Name:Flucloxacillin
CAS:5250-39-5
Purity:98% Remarks:AB07956 More... - CB Index:64
- Related Information:Catalog(42958)
- Company Name:XiaoGan ShenYuan ChemPharm co,ltd
- Tel: 15527768850
- Products Intro:CAS:5250-39-5
More... - CB Index:52
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- Company Name:Shanghai G&K Biomedical Scientific Inc.
- Tel:021-34502253 13391330186
- Products Intro:Product Name:Fluchlxacillin
CAS:5250-39-5
Purity:API Package:1kg;10kg;25kg More... - CB Index:52
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- Company Name:Raw material medicin reagent co.,Ltd
- Tel:
- Products Intro:Product Name:Flucloxacillin
CAS:5250-39-5
Purity:95% Package:--- More... - CB Index:58
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- Company Name:Conier Chem & Pharma Limited
- Tel: 13368167990
- Products Intro:CAS:5250-39-5
Purity:99% HPLC Package:5KG;1KG - CB Index:58
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