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Tocainide hydrochloride

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Tocainide hydrochloride,2-amino-2' ,6 '-propionoxyxylidide hydrochloride (Tonocard)(pKa 7.7), is an analog of lidocaine. It is orally active and haselectrophysiological properties like those of lidocaine. Totalbody clearance of tocainide hydrochloride is only166 mL/min, suggesting that hepatic clearance is not large.Because of low hepatic clearance, the hepatic extraction ratiomust be small; therefore, tocainide hydrochloride is unlikelyto be subject to a substantial first-pass effect. The drug differsfrom lidocaine, in that it lacks two ethyl groups, which providestocainide hydrochloride some protection from first-passhepatic elimination after oral ingestion. Tocainide hydrochlorideis hydrolyzed in a manner similar to that of lidocaine.None of its metabolites is active.
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  • Company Name:Shanxi New Baoyuan Pharmaceutical Co., Ltd.
  • Tel:0352-7606558
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  • Company Name:Shanghai Chaolan Chemical Technology Center
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  • Products Intro:Product Name:Tocainide.HCl
    CAS:35891-93-1
    Purity:98% Package:5MG;10MG;50MG;100MG,1G,5G,100G
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  • Company Name:Beijing Solarbio Science & Tecnology Co., Ltd.
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    Package:125mg More...
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  • Company Name:ANHUI WITOP BIOTECH CO., LTD
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  • Company Name:Dideu Industries Group Limited
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  • Products Intro:Product Name:Tocainide hydrochloride
    CAS:35891-93-1
    Purity:99.9% Package:1g;1.1USD Remarks:FDA GMP CEP Approved Manufacturer
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  • Company Name:Shaanxi Dideu Medichem Co. Ltd
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  • Products Intro:Product Name:Tocainide hydrochloride USP/EP/BP
    CAS:35891-93-1
    Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
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