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(S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE

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USE
Selective and potent GLU K5 (GluR5)-subunit containing kainate receptor antagonist (apparent K D = 402 nM); active enantiomer of UBP 296 ((RS)-1-(2-Amino-2-carboxyethyl)-3-(2-carboxybenzyl)pyrimidine-2,4-dione ). Displays ~ 260-fold selectivity over AMPA receptors. UBP 296 displays ~ 90-fold selectivity over recombinant human GLU K6 - and GLU K2 -containing kainate receptors, has little or no action at NMDA or group I mGlu receptors and selectively blocks kainate receptor-mediated LTP induction in rat hippocampal mossy fibres.

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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
  • Tel:821-50328103-801 18930552037
  • Products Intro:Product Name:UBP 302;(S)-1-(2-AMino-2-carboxyethyl)-3-(2-carboxybenzyl)pyriMidine-2,4-dione
    Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
  • CB Index:69
  • Related Information:Catalog(15848)
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  • Company Name:MedBioPharmaceutical Technology Inc
  • Tel:021-69568360 18916172912
  • Products Intro:Product Name:(S)-1-(2-AMINO-2-CARBOXYETHYL)-3-(2-CARBOXYBENZYL)PYRIMIDINE-2,4-DIONE
    CAS:745055-91-8
    Purity:98% Package:10mg; 50mg Remarks:Medbio
  • CB Index:58
  • Related Information:Catalog(8141)
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  • Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
  • Tel:010-60605840
  • Products Intro:Product Name:UBP302
    CAS:745055-91-8
    Purity:98% Package:5mg
  • CB Index:58
  • Related Information:Catalog(29778)
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