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Norepinephrine

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51-41-2 Basic informationMore
USE
Norepinephrine (NE, Levophed) differs from DA onlyby addition of a 1-OH substituent (β-OH-DA) and from Eonly by lacking the N-methyl group. Like DA, it is polar andrapidly metabolized by both COMT and MAO, resulting inpoor oral bioavailability and short DOA (1 or 2 minutes evenwhen given intravenously). It is a stimulant of α1-, α2-, andβ1-adrenoceptors (notice that lacking the N-methyl group resultsin lacking β2- and β3-activity). It is used to counteractvarious hypotensive crises, because its α-activity raisesblood pressure and as an adjunct treatment in cardiac arrestbecause its β-activity stimulates the heart. It has limitedclinical application caused by the nonselective nature of itsactivities.
Lastest Price from Norepinephrine manufacturers
  • Norepinephrine
  • US $125.00-45.00/Kg/Bag
  • CAS:51-41-2
  • Min. Order: 1Kg/Bag
  • Purity: 0.99
  • Supply Ability: 20 tons
  • 2024-04-22
  • Norepinephrine
  • US $0.00-0.00/KG
  • CAS:51-41-2
  • Min. Order: 1KG
  • Purity: 99
  • Supply Ability: 50000KG/month
  • 2024-03-19

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