URB754
86672-58-4 Basic informationMore
- Product Name:URB754
- Synonyms: URB754 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazine-4-one 6-Methyl-2-[(4-methylphenyl)amino]-4H-3,1-benzoxazin-4-one 6-Methyl-2-(p-tolylMino)-4H-benzo[d][1,3]oxazin-4-one 6-Methyl-2-(p-tolylaMino)-1H-benzo[d][1,3]oxazin-4(2H)-one 6-Methyl-2-(p-tolylaMino)-4H-benzo[d][1,3]oxazin-4-one 6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one URB754, >=98%
- CAS:86672-58-4
- MF:C16H14N2O2
- MW:266.3
- EINECS:
- Mol File:86672-58-4.mol
-
USE
URB754 is a potent, noncompetitive inhibitor of MGL, exhibiting an IC50 of 200 nM for the recombinant rat brain enzyme. It inhibits rat brain fatty acyl amide hydrolase (FAAH) less effectively with an IC50 of 32 μM and binds weakly to the rat CB1 receptor with an IC50 of 3.8 μM. It does not inhibit cyclooxygenase-1 (COX-1) or COX-2 at concentrations up to 100 μM. Inhibition of 2-AG hydrolysis is associated with enhanced stress-induced analgesia and may represent a novel drug target in pain and stress management.
Lastest Price from URB754 manufacturers
- URB754
-
- $7.00 /KG
- CAS:86672-58-4
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 100kg
- 2020-02-19
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:18210857532 18210857532
- Products Intro:Product Name:URB754
CAS:86672-58-4
Package:250Mg,25Mg More... - CB Index:76
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- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
- Products Intro:Product Name:6-Methyl-2-(p-tolylamino)-4H-3,1-benzoxazin-4-one
CAS:86672-58-4
Purity:95.0% LC Package:10MG,50MG More... - CB Index:81
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- Company Name:Chemsky（shanghai）International Co.,Ltd.
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CAS:86672-58-4
Purity:98% More... - CB Index:50
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- Products Intro:Product Name:URB-754
CAS:86672-58-4
Purity:98%(HPLC) More... - CB Index:66
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- Company Name:NCE Biomedical Co.,Ltd.
- Tel:4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988
- Products Intro:Product Name:URB754
CAS:86672-58-4
Purity:99% HPLC Package:50Mg,100Mg,500Mg,1g,5g,10g,50g,100g,500g,1kg Remarks:XYA0559 More... - CB Index:55
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- Products Intro:Product Name:URB 754
CAS:86672-58-4
Purity:98% Package:50kg;25kg;10kg;5kg;500g;500mg; More... - CB Index:58
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- Company Name:Nanjing Norris-Pharm Technology Co., Ltd
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- Products Intro:Product Name:URB754
CAS:86672-58-4
Purity:0.95 Package:5KG;1KG;100G More... - CB Index:55
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