EAI-045

• Product Name:EAI-045
• Synonyms: EAI-045 2-(5-fluoro-2-hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)-N-(thiazol-2-yl)acetamide EA1045 α-(5-fluoro-2-hydroxyphenyl)-1,3-dihydro-1-oxo-N-2-thiazolyl-2H-Isoindole-2-acetamide EAI 045;EAI-045 CS-2350 EAI045;EAI 045;EAI-045 N-(3-((5-fluoroethoxy)phenyl)amino)pyrimidin-4-yl)amino)phenyl)acrylamide (EAI-045)
• CAS:1942114-09-1
• MF:C19H14FN3O3S
• MW:383.4
• EINECS:
• Mol File:1942114-09-1.mol
• 

EAI045 is a potent and selective EGFR inhibitor (fourth generation). EAI045 targets selected drug-resistant EGFR mutants without affecting the wild-type receptor. EAI045 inhibits L858R/T790M-mutant EGFR with low-nanomolar potency in biochemical assays. Therefore, it is a potential candidate drug for the treatment of related non-small cell lung cancer (NSCLC). It should be noted that EAI-045 is effectively in targeting the EGFR C797S mutation, which is resistance to the third-generation EGFR inhibitors including AZD9291 (osimertinib) and CO-1686 (rociletinib).

• Company Name:Dalian Meilun Biotech Co., Ltd.
• Tel:0411-62910999 13889544652
• Products Intro:Product Name:EAI045
  CAS:1942114-09-1
  Purity:>98%,BR Package:10MG;50MG; Remarks:MB3394
• CB Index:58
• Related Information:Catalog(4727)

• Company Name:TargetMol Chemicals Inc.
• Tel:021-021-33632979 15002134094
• Products Intro:Product Name:EAI045
  CAS:1942114-09-1
  Purity:99.73% Package:50mg/RMB 1255;100mg/RMB 1997;10mg/RMB 491 More...
• CB Index:58
• Related Information:Catalog(7783)

• Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
• Tel:18149758185 18149758185
• Products Intro:Product Name:EAI-045
  CAS:1942114-09-1
  Purity:98% Package:10mg;100mg;1g;10g;100g;1kg Remarks:57.47 More...
• CB Index:58
• Related Information:Catalog(3466)

• Company Name:Mashilabs (Shanghai) Co.,Ltd.
• Tel: 19916721580
• Products Intro:CAS:1942114-09-1
  Purity:98%
• CB Index:58
• Related Information:Catalog(4295)