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112665-43-7

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112665-43-7 Basic informationMore
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Seratrodast, a novel benzoquinone derivative, is the first thromboxane A<sub>2</sub> (TxA<sub>2</sub>) receptor antagonist to reach the market. It is orally active for the treatment of bronchospastic disorders such as asthma. TxA<sub>2</sub>, a metabolite of the arachidonate cascade, is involved in several cardiovascular and respiratory diseases through its potent biological effects on platelet aggregation and constriction of vascular and respiratory smooth muscles. Seratrodast potently inhibits platelet aggregation and bronchoconstriction induced by a TxA<sub>2</sub> mimic and by a variety of spasmogenic prostanoids including PGF<sub>2α</sub>, PGD<sub>2</sub> and 9α,11β-PGF<sub>2</sub>. Seratrodast shows excellent efficacy in asthma and has been reported to be potentially useful in hyper-responsive disorder. The R-(+)- seratrodast was reported to be the active isomer.
Lastest Price from Seratrodast manufacturers
  • Seratrodast
  • US $0.01-1.00/KG
  • CAS:112665-43-7
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50 tons
  • 2020-04-25

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  • Company Name:J & K SCIENTIFIC LTD.
  • Tel:400-666-7788 010-82848833-
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  • Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456-
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    Remarks:C14164 More...
  • CB Index:61
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  • Company Name:TCI (Shanghai) Development Co., Ltd.
  • Tel:021-67121386 / 800-988-0390
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  • Company Name:Shanghai Sunway Pharmaceutical Technology Co., Ltd
  • Tel: 021-51613915-
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  • Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
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