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721-50-6

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721-50-6 Basic informationMore
USE
Prilocaine metabolism has beenstudied extensively in animal models, less is known aboutthe human metabolites or the human CYP enzymes involvedin their formation . The metabolism of prilocainein the liver yields o-toluidine, which is a possiblecarcinogen. Many aromatic amines, including o-toluidinehave been shown to be mutagenic, and metabolites of otoluidinehave been shown to form DNA adducts.Metabolites of o-toluidine are also believed to be responsiblefor the methemoglobinemia observed with prilocaineuse. To decrease the potential for methemoglobinemia, strictadherence to the maximum recommended dose should befollowed. Metabolism of prilocaine is extensive with lessthan 5% of a dose excreted unchanged in the urine.
Lastest Price from Prilocaine manufacturers
  • Prilocaine
  • US $10.00 /ASSAYS
  • CAS:721-50-6
  • Min. Order: 1KG
  • Purity: ≥99%
  • Supply Ability: 1 Metric Ton/Month
  • 2020-06-19
  • Prilocaine
  • US $90.00 /g
  • CAS:721-50-6
  • Min. Order: 10g
  • Purity: 99.8%
  • Supply Ability: 1000kg
  • 2020-05-10

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