Niraparib
1038915-60-4 Basic informationMore
- Product Name:Niraparib
- Synonyms: MK-4827,(S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxaMide Niraparib 2-[4-((3S)-3-Piperidinyl)phenyl]-2H-indazole-7-carboxamide MK4827 (Niraparib) 2H-Indazole-7-carboxamide, 2-[4-(3S)-3-piperidinylphenyl]- (S)-2-(4-(piperidin-3-yl)phenyl)-2H-indazole-7-carboxamide hydrocholoride 2-[4-(3S)piperidin-3-ylphenyl]-2H-indazol-7-carboxamide 2-[4-[(3s)-piperidin-3-yl]phenyl]indazole-7-carboxamide
- CAS:1038915-60-4
- MF:C19H20N4O
- MW:320.39
- EINECS:
- Mol File:1038915-60-4.mol
-
USE
The synthesis and initial pharmacology of niraparib have been published. Niraparib has affinity for PARP 1 and 2 inhibition (IC50 = 3.8 and 2.1 nM, respectively) and inhibits the proliferation of cancer cells with mutant BRCA1 and BRCA2 with IC50 values in the 10–100 nM range in vitro. Niraparib demonstrated efficacy as a single agent in a xenograft model of BRCA1-deficient cancer. Niraparib has also been reported to act as a preclinical radiosensitiser and has entered into clinical oncology trials.
Lastest Price from Niraparib manufacturers
- Niraparib
-
- US $0.00-0.00/mg
- CAS:1038915-60-4
- Min. Order: 10mg
- Purity: 0.98
- Supply Ability: 10g
- 2025-02-05
- Niraparib
-
- US $0.00-0.00/g
- CAS:1038915-60-4
- Min. Order: 10000g
- Purity: 99% HPLC
- Supply Ability: 1000kg
- 2025-01-31
Browse by Nationality 1038915-60-4 Suppliers >Global suppliers
Beijing (9) Shanghai (71) Tianjin (1) Chongqing (2) Sichuan (6) Guangdong (17) Zhejiang (25) Hubei (48) Shandong (21) Henan (10) Hebei (8) Liaoning (1) Anhui (6) Jiangsu (42) Jiangxi (1) Shaanxi (7) Hong Kong (5) Other (1) Member (280) All (281)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Nanjing Qiya Pharmaceutical Co., Ltd.
- Tel:025-85451006; 18795969897
- Products Intro:Product Name:Niraparib
CAS:1038915-60-4
Purity:99.5%HPLC Package:1g;10g;100g;1kg More... - CB Index:58
- Related Information:Catalog(83)
- Company Name:Anhui nuoquan pharmaceutical co. LTD
- Tel:0556-5032870 15705561919
- Products Intro:Product Name:niraparib
CAS:1038915-60-4
Purity:99%，Single impurity less than 0.15% Package:10g,100g More... - CB Index:55
- Related Information:Catalog(95)
- Company Name:CHANGZHOU PHARMACEUTICAL FACTORY
- Tel:519-88821493 18915891730
- Products Intro:Product Name:Niraparib
CAS:1038915-60-4
Purity:99% HPLC Package:1kg - CB Index:58
- Related Information:Catalog(163)
- Company Name:Hangzhou Runyan Medical Technology Co., LTD
- Tel:13989459766 17767198890
- Products Intro:Product Name:Niraparib
CAS:1038915-60-4
Purity:99% HPLC Package:1G;10G;100G;1KG;10KG;100KG - CB Index:58
- Related Information:Catalog(428)
- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
- Products Intro:Product Name:Niraparib (MK4827)
CAS:1038915-60-4
Purity:98%+ HPLC Package:50mg;100mg;500mg;1g;5g;10g Remarks:Biochemical Reagents; Pharmaceutical Intermediates More... - CB Index:61
- Related Information:Catalog(6005)