Sitafloxacin
127254-12-0 Basic informationMore
- Product Name:Sitafloxacin
- Synonyms: spifloxacin 7-[(4S)-4-Amino-6-azaspiro[2.4]heptan-6-yl]-8-chloro-6-fluoro-1-[(2S)-2-fluorocyclopropyl]-4-oxoquinoline-3-carboxylic acid 3-Quinolinecarboxylic acid, 7-[(7S)-7-aMino-5-azaspiro[2.4]hept-5-yl]-8-chloro-6-fluoro-1-[(1R,2S)-2-fluorocyclopropyl]-1,4-dihydro-4-oxo- Sitafloxacin anhydrous 7-((S)-7-Amino-5-azaspiro[2.4]heptan-5-yl)-8-chloro-6-fluoro-1-((1R,2S)-2-fluorocyclopropyl)-4 Sitafloxacfn Sitfloxacfn Sitafloxacin-d4
- CAS:127254-12-0
- MF:C19H18ClF2N3O3
- MW:409.81
- EINECS:1308068-626-2
- Mol File:127254-12-0.mol
-
USE
As a class, the major adverse events for fluoroquinolones are cardiac arrhythmia (due to QT interval 622 Shridhar Hegde and Michelle Schmidt prolongation), major phototoxicity, CNS disturbances (seizures, dizziness, and headaches), and tendonitis. The GI side effects, common to most antimicrobials, include Clostridium difficile-associated diarrhea (CDAD) and alterations in glucose homeostasis. From the clinical safety profile of sitafloxacin (1,059 patients receiving either 50 mg b.i.d. or 100 mg b.i.d.), about a third of patients experienced an adverse event with the most common being diarrhea, liver enzyme elevations, and headaches; however, the risk of QT prolongation, hypoglycemia, and hepatotoxicity were all considered to be low. Phototoxicity appears to be the limiting toxicity, particularly in non-Asian patients.
Lastest Price from Sitafloxacin manufacturers
- Sitafloxacin
-
- US $200.00 /kg
- CAS:127254-12-0
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000kg/Months
- 2023-06-26
- Sitafloxacin
-
- US $1.10 /g
- CAS:127254-12-0
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- 2021-07-20
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- Company Name:Hubei kangen Pharmaceutical Chemical Co., Ltd
- Tel:15337215803 15337215803
- Products Intro:Product Name:Sitafloxacin
CAS:127254-12-0
Purity:99 Package:100g;1kg;10kg;25kg Remarks:1000g More... - CB Index:56
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
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CAS:127254-12-0
Remarks:C14171 More... - CB Index:61
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- Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel:0571-82693216
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- Company Name:BioBioPha Co., Ltd.
- Tel:0871-65217109 13211707573;
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CAS:127254-12-0
Purity:98.5% Package:5mg Remarks:BBP81248 More... - CB Index:65
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- Company Name:ChemStrong Scientific Co.,Ltd
- Tel:0755-0755-66853366 13670046396
- Products Intro:Product Name:Sitafloxacin
Purity:95% HPLC Package:10mg;25mg;50mg;100mg More... - CB Index:56
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