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Selumetinib

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606143-52-6 Basic informationMore
USE
In phase II clinical trials of radioiodine-refractory papillary thyroid carcinoma, 39 patients took daily oral doses of Selumetinib (100mg bid) for 28 days; results showed that 21 patients’ conditions stabilized (54%), 11 patients’ conditions worsened (28%), 49% patients’ conditions were stable for 16 weeks, 36% patients’ conditions were stable for 24 weeks, and survival terms did not progress to 32 weeks. Negative reactions mainly consisted of rashes (59%), diarrhea (44%), and weakness (41%). Some studies found that after treating 20 patients with thyroid cancer with Selumetinib (75mg bid) for 4 weeks, Selumetinib increased the iodine uptake and retention of patients with radioiodine-refractory papillary thyroid carcinoma. In a blind and random comparative study between a Selumetinib and Docetaxel (DOC) combination treatment group and DOC and placebo treatment group for 87 mutant NSCLSC patients, survival times were 9.4 months and 5.2 months, PFS were 5.3 months and 2.1 months, RR were 37% and 0%, thus showing dramatic differences. Selumetinib’s main negative reactions include neutrophil depletion, dermatitis, and respiratory failure.
Lastest Price from Selumetinib manufacturers
  • Selumetinib
  • US $10.00 /KG
  • CAS:606143-52-6
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
  • 2022-12-05
  • SeluMetinib
  • US $0.00 /gram
  • CAS:606143-52-6
  • Min. Order: 1gram
  • Purity: 99%
  • Supply Ability: 10kg
  • 2022-02-18

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  • Company Name:Hubei Junxian Biotechnology Co., Ltd
  • Tel: 18908622922
  • Products Intro:Product Name:Selumetinib
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  • Company Name:J & K SCIENTIFIC LTD.
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  • Company Name:Chembest Research Laboratories Limited
  • Tel:021-20908456
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    Remarks:C14159 More...
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  • Company Name:BeiJing Hwrk Chemicals Limted
  • Tel:0757-86329057 18516978288
  • Products Intro:Product Name:Selumetinib
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