Panitumumab
339177-26-3 Basic informationMore
- Product Name:Panitumumab
- Synonyms: Panitumumab Abx-egf Abx-egf mab Immunoglobulin, anti-(human epidermal growth factor receptor) (human monoclonal abx-egf heavy chain), disulfide with human monoclonal abx-egf light chain, dimer Unii-6A901E312a Vectibix Abenix Panitumumab USP/EP/BP
- CAS:339177-26-3
- MF:
- MW:0
- EINECS:
- Mol File:Mol File
-
USE
Panitumumab is a recombinant, fully human IgG2 kappa monoclonal antibody
that is highly selective for the epidermal growth factor receptor (EGFR),
and it is indicated for the treatment of EGFR-expressing, metastatic colorectal
carcinoma (mCRC) with disease progression on or following fluoropyrimidine-,
oxaliplatin-, and irinotecan-containing chemotherapy regimens. Overexpression
of EGFR is detected in many human cancers, including those of the colon and
rectum. Panitumumab blocks the binding of ligands such as epidermal growth
factor (EGF) and transforming growth factor (TGF-a) to various EGFR-expressing
cell lines, which results in inhibition of EGF-dependent tumor cell activation,
induction of apoptosis, and decreased pro-inflammatory cytokine and vascular
growth factor production. In vitro, panitumumab binds EGFR with high affinity
(KD ? 50pM; IC50 ? 3 nM) in human cervical epidermal cell line A-431.
.
Lastest Price from Panitumumab manufacturers
- Panitumumab
-
- US $1.10 /g
- CAS:339177-26-3
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- 2021-07-03
Browse by Nationality 339177-26-3 Suppliers >Global suppliers
Beijing (1) Shanghai (14) Tianjin (1) Sichuan (1) Zhejiang (2) Hunan (1) Hubei (19) Liaoning (1) Anhui (2) Jiangsu (2) Jiangxi (1) Shaanxi (2) Member (47) All (47)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Wuhan Chemstan Biotechnology Co., Ltd.
- Tel: 15926423062
- Products Intro:Product Name:Panitumumab
Purity:>95%;1mg/ml Package:200ug;500ug;1mg - CB Index:58
- Related Information:Catalog(10132)
- Company Name:Wuhan Sunrise Technology Development Co., Ltd.
- Tel:027-027-83314682 13554138826
- Products Intro:Product Name:Panitumumab
CAS:339177-26-3
Purity:97% (API) Package:2mg/vial ， for other packages pls just contact for details More... - CB Index:62
- Related Information:Catalog(300)
- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:Panitumumab
CAS:339177-26-3
Purity:>95% Package:5MG - CB Index:58
- Related Information:Catalog(4647)
- Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
- Tel: 18149758185
- Products Intro:Product Name:Panitumumab
CAS:339177-26-3
Purity:98% Package:10mg;100mg;1g;10g;100g;1kg - CB Index:58
- Related Information:Catalog(3421)
- Company Name:Taizhou KEDE Chemical Co., Ltd
- Tel:0576-84613060 13093829633
- Products Intro:Product Name:Panitumumab
CAS:339177-26-3
Purity:98% Package:g - CB Index:60
- Related Information:Catalog(298)
- Company Name:Shanghai Lollane Biological Technology Co.,Ltd.
- Tel:021-52996696，15000506266 15000506266
- Products Intro:Product Name:Panitumumab
Purity:98% HPLC Package:5mg，10mg，50mg，100mg，1g，5g - CB Index:55
- Related Information:Catalog(4121)