Moxonidine
75438-57-2 Basic informationMore
- Product Name:Moxonidine
- Synonyms: MOXONIDINE MOXONIDINE HCL 4-chloro-n-(4,5-dihydro-1h-imidazol-2-yl)-6-methoxy-2-methyl-5-pyrimidinamin bdf5895 be5895 BDF-5895 HCL 4-CHLORO-6-METHOXY-2-METHYL-5-(2-IMIDAZOLIN-2-YL)AMINOPYRIMIDINE HCL 4-CHLORO-N-(4,5-DIHYDRO-1H-IMIDAZOL-2-YL)-6-METHOXY-2-METHYL-5-PYRIMIDINAMINE HYDROCHLORIDE
- CAS:75438-57-2
- MF:C9H12ClN5O
- MW:241.68
- EINECS:629-833-3
- Mol File:75438-57-2.mol
-
USE
Moxonidine, also known as Physiotens, is a highly selective imidazoline receptor agonist-Ⅰ by excitement ventrolateral medulla nucleus (RVLM)-Ⅰ type imidazoline receptor in the peripheral sympathetic nerve activity decreased. This receptor subtype is found in both the rostral ventro-lateral pressor and ventromedial depressor areas of the medulla oblongata. <br />
Moxonidine therefore causes a decrease in sympathetic nervous system activity and, therefore, a decrease in blood pressure. <br />
It is a new type of antihypertensive drug, commonly used in the treatment of essential hypertension. Compared to the older central-acting antihypertensives, moxonidine binds with much greater affinity to the imidazoline I1-receptor than to the α2-receptor. In contrast, clonidine binds to both receptors with equal affinity.<br />
It may have a role when thiazides, beta-blockers, ACE inhibitors and calcium channel blockers are not appropriate or have failed to control blood pressure.
Lastest Price from Moxonidine manufacturers
- Moxonidine
-
- US $0.00 /Kg/Bag
- CAS:75438-57-2
- Min. Order: 50g
- Purity: 97.5%-102%
- Supply Ability: 1000g
- 2024-11-22
- Moxonidine
-
- US $0.00 /kg
- CAS:75438-57-2
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20tons
- 2024-04-08
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Moxonidine
CAS:75438-57-2
Package:250Mg,25Mg More... - CB Index:76
- Related Information:Catalog(94657)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:Moxonidine hydrochloride;4-Chloro-N-(4,5-dihydro-1H-iMidazol-2-yl)-6-Methoxy-2-Methyl-5-pyriMidinaMinehydrochloride
CAS:75438-57-2
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
- Products Intro:Product Name:Moxonidine
CAS:75438-57-2
Purity:98.0% T Package:1G,200MG More... - CB Index:81
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- Company Name:Jia Xing Isenchem Co.,Ltd
- Tel:0573-85285100 18627885956
- Products Intro:CAS:75438-57-2
Purity:98% (HPLC or GC) Package:25g,100g,500g;1kg More... - CB Index:66
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- Company Name:Adamas Reagent, Ltd.
- Tel:400-6009262 16621234537
- Products Intro:Product Name:Moxonidine
CAS:75438-57-2
Purity:对照品 Package:10mg~500mg Remarks:AC001428000 - CB Index:59
- Related Information:Catalog(14103)
- Company Name:XiaoGan ShenYuan ChemPharm co,ltd
- Tel: 15527768850
- Products Intro:CAS:75438-57-2
More... - CB Index:52
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- Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
- Tel:0571-82693216
- Products Intro:Product Name:Moxonidine
CAS:75438-57-2
More... - CB Index:52
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