Esomeprazole magnesium
161973-10-0 Basic informationMore
- Product Name:Esomeprazole magnesium
- Synonyms: MagnesiuM,bis[6-Methoxy-2-[(S)-[(4-Methoxy-3,5-diMethyl-2-pyridinyl)Methyl]sulfinyl-kO]-1H-benziMidazolato-kN3]-, (T-4)- ESOMEPRAZOLE MAGNESIUM/SODIUM (T-4)-bis[6-methoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl-κO]-1H-benzimidazolato-κN3]-magnesium 5-Methoxy-2-((S)-((4-Methoxy-3,5-diMethyl-2-pyridyl)Methyl)sulfinyl-1H-benziMidazole MagnesiuM salt ESOMEPRAZOLE MAGNESIUM SAMPLE Esomeprazole magnesium Magnesium 5-methoxy-2-[(4-methoxy-3,5-dimethylpyridin-2-yl)methylsulfinyl]benzimidazol-1-ide Bis(5-methoxy-2-{(S)-[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl}benzimidazol-1-ide) magnesium
- CAS:161973-10-0
- MF:C34H36MgN6O6S2
- MW:713.12
- EINECS:627-029-7
- Mol File:161973-10-0.mol
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USE
Esomeprazole magnesium,S-bis(5-rnethoxy-2-[(S)-[(4-methoxy-3,5-dimethyl-2-pyridinyl)methyl]sulfinyl]-1H-benzimidazole-l-yl) magnesiumtrihydrate (Nexium), is the S-enantiomer ofomeprazole. The benzimidazole PPIs contain a chiral sulfuratom that form an enantiomeric pair that is stable andinsoluble under standard conditions. The S-isomer ofomeprazole has slightly greater PPI activity, and its intrinsicclearance is approximately three times lower thanthat of R-omeprazole (15 vs. 43μL/min). The lowerclearance of S-omeprazole is related to slower metabolicclearance by the CYP2C19 isozyme. Although Romeprazoleis primarily transformed to the 5-hydroxymetabolite, the S-isomer is metabolized by O-demethylationand sulfoxidation, which contribute little to intrinsicclearance.
Lastest Price from Esomeprazole magnesium manufacturers
- Esomeprazole magnesium
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- US $0.00-0.00/kg
- CAS:161973-10-0
- Min. Order: 1kg
- Purity: EP/USP
- Supply Ability: 1KG
- 2024-11-01
- Esomeprazole magnesium
-
- US $0.00 /kg
- CAS:161973-10-0
- Min. Order: 1kg
- Purity: 98% HPLC
- Supply Ability: 500 kgs
- 2024-09-09
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
- Products Intro:Product Name:EsoMeprazole MagnesiuM
CAS:161973-10-0
Remarks:C13643 More... - CB Index:61
- Related Information:Catalog(6005)
- Company Name:Shanghai Hanhong Scientific Co.,Ltd.
- Tel:021-54306202 13764082696
- Products Intro:Product Name:Esomeprazole magnesium
CAS:161973-10-0
Purity:0.97 Remarks:AB07552 More... - CB Index:64
- Related Information:Catalog(42958)
- Company Name:XiaoGan ShenYuan ChemPharm co,ltd
- Tel: 15527768850
- Products Intro:CAS:161973-10-0
More... - CB Index:52
- Related Information:Catalog(8837)
- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-400-6206333 18521732826
- Products Intro:Product Name:Esomeprazole Magnesium
CAS:161973-10-0
Purity:98% Package:100mg/RMB 576.00;200mg/RMB 823.00;25mg/RMB 278.00 More... - CB Index:65
- Related Information:Catalog(25003)