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Benzonitrile

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Benzonitrile is mainly hydroxylated in vivo to cyanophenols, a small amount being hydrolysed to benzoic acid (Williams 1959). Benzonitrile also forms 6>-hydroxybenzonitrile, m-hydroxybenzonitrile, and /p-hydroxybenzonitrile in rabbits (HSDB 1988). In rabbit, 50% of a dose of 150 mg/kg was converted to conjugated cyanophenols and 10% of the benzonitrile fed was excreted as benzoic acid. Hydrogen cyanide is not a metabolite of benzonitrile (Williams 1959) and cyanide was not found to be formed by benzonitrile either in vivo or in vitro (Tanii and Hashimoto 1984). The in vivo microsomal hydroxylation of specifically deuterated benzonitrile in the rat yielded mainly 4-hydroxybenzonitrile with 41% retention of deuterium (Daly et al 1968).
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  • Benzonitrile
  • US $0.00-0.00/kg
  • CAS:100-47-0
  • Min. Order: 200kg
  • Purity: 99.75
  • Supply Ability: 99999
  • 2023-12-18
  • Benzonitrile
  • US $0.00 /KG
  • CAS:100-47-0
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 50000KG/month
  • 2023-09-14

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  • Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
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    CAS:100-47-0
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    Purity:98% Package:10g;50g;100g;250g;500g More...
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