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Cefuroxime

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USE
Cefuroxime axetil (Ceftin) is the 1-acetyoxyethyl ester ofcefuroxime. During absorption, this acid-stable, lipophilic,oral prodrug derivative of cefuroxime is hydrolyzed to cefuroximeby intestinal and/or plasma enzymes. The axetilester provides an oral bioavailability of 35% to 50% of cefuroxime,depending on conditions. Oral absorption of theester is increased by food but decreased by antacids and histamineH2-antagonists. The latter effect may be because ofspontaneous hydrolysis of the ester in the intestine becauseof the higher pH created by these drugs. Axetil is used forthe oral treatment of non–life-threatening infections causedby bacteria that are susceptible to cefuroxime. The prodrugform permits twice-a-day dosing for such infections.
Lastest Price from Cefuroxime manufacturers
  • Cefuroxime
  • US $0.00-0.00/Kg/Drum
  • CAS:55268-75-2
  • Min. Order: 1KG
  • Purity: 98%min
  • Supply Ability: 500kg
  • 2024-12-13
  • Cefuroxime acid
  • US $10.00 /KG
  • CAS:55268-75-2
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 10 mt
  • 2024-11-21

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