Papaverine hydrochloride

• Product Name:Papaverine hydrochloride
• Synonyms: Papaverine hydrochloride, 99% 5GR papaverine hydrochloride:6,7-dimethoxy-1-(3,4-dimethoxybenzyl)-isoQUINOLINE hydrochloride: 1-(3,4-dimethoxybenzyl)-6,7-dimethoxyisoQUINOLINE hydrochloride Papaverine hydrochloride,99% papaverin hydrochloride papaverine hydrochloride 90.2% Papaverine Hydrochloride (200 mg) Isoquinoline,1-[(3,4-diMethoxyphenyl)Methyl]-6,7-diMethoxy-, hydrochloride (1:1) 1-[(3',4'-DIMETHOXYPHENYL)METHYL]-6,7-DIMETHOXYISOQUINOLINE HCL
• CAS:61-25-6
• MF:C20H22ClNO4
• MW:375.85
• EINECS:200-502-1
• Mol File:61-25-6.mol
• 

Papaverine hydrochloride,6,7-dimethoxy-1-veratrylisoquinoline hydrochloride,was isolated by Merck in 1848 from opium,in which it occurs to the extent of about 1%. Althoughits natural origin is closely related to morphine, the pharmacologicalactions of papaverine hydrochloride areunlike those of morphine. Its main effect is as a spasmolyticon smooth muscle, acting as a direct, nonspecificrelaxant on vascular, cardiac, and other smooth muscle.Because of its broad antispasmodic action on ACh muscarinicreceptors, it is often called a nonspecific antagonist.Papaverine hydrochloride has been used in the treatmentof peripheral vascular disorders, but its use is limitedby lack of potency.<br/> Papaverine hydrochloride interferes with the mechanismof muscle contraction by inhibiting the cyclic nucleotidephosphodiesterases in smooth muscle cells responsible forconverting cAMP and cyclic guanosine monophosphate(cGMP) to 5' -AMP and 5' -GMP, respectively. The increasedlevels of cAMP and cGMP are associated with muscle relaxation through their phosphorylation of myosinlight-chain kinase.<p>PAPAVERINE HYDROCHLORIDE is Crystalline Solid</p> Papaverine hydrochloride,6,7-dimethoxy-1-veratrylisoquinoline hydrochloride,was isolated by Merck in 1848 from opium,in which it occurs to the extent of about 1%. Althoughits natural origin is closely related to morphine, the pharmacologicalactions of papaverine hydrochloride areunlike those of morphine. Its main effect is as a spasmolyticon smooth muscle, acting as a direct, nonspecificrelaxant on vascular, cardiac, and other smooth muscle.Because of its broad antispasmodic action on ACh muscarinicreceptors, it is often called a nonspecific antagonist.Papaverine hydrochloride has been used in the treatmentof peripheral vascular disorders, but its use is limitedby lack of potency.<br> Papaverine hydrochloride interferes with the mechanismof muscle contraction by inhibiting the cyclic nucleotidephosphodiesterases in smooth muscle cells responsible forconverting cAMP and cyclic guanosine monophosphate(cGMP) to 5' -AMP and 5' -GMP, respectively. The increasedlevels of cAMP and cGMP are associated with muscle relaxation through their phosphorylation of myosinlight-chain kinase.

• Company Name:Qinghai Pharmaceutical Factory Co., Ltd.
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• CB Index:58
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• Company Name:Zhejiang Boxiao Bio-Pharmaceutical Co., Ltd.
• Tel:0571-63280982
• Products Intro:Product Name:Papaverine Hydrochloride
  CAS:61-25-6
  Purity:>=99.9% Package:根据客户要求
• CB Index:58
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• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:Papaverine Hydrochloride
  CAS:61-25-6
  Purity:99% Package:1g,50g,5g More...
• CB Index:76
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• Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
• Tel:021-61259108 18621169109
• Products Intro:Product Name:Papaverine hydrochloride
  CAS:61-25-6
  Purity:99% Remarks:20722 More...
• CB Index:62
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• Company Name:Energy Chemical
• Tel:021-021-58432009 400-005-6266
• Products Intro:Product Name:Papaverine hydrochloride
  CAS:61-25-6
  Purity:99% Package:25g,5g More...
• CB Index:61
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