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Atosiban

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90779-69-4 Basic informationMore
USE
Atosiban was introduced in the UK as an injectable inhibitor of preterm labor, a major cause of infant morbidity and mortality. This peptidic oxytocin analog is an antagonist of the vasopressin V<sub>1a</sub> receptor and of the oxytocin receptor which is found in dramatically increased concentration in the uterine myometrium of pregnant women near term. It competitively inhibited contractions in the pregnant guinea pig uterus induced by oxytocin and vasopressin. In a multicenter, double-blind, placebo-controlled trial, treatment with atosiban caused pregnancy prolongation for up to 7 days in women with more than 28 weeks of gestation. In a comparative clinical trial, atosiban showed a comparable tocolytic action (uterine relaxant) to ritodrine but the former was significantly better tolerated, especially with regards to maternal cardiovascular side effects. In healthy volunteers, plasma levels of atosiban decreased bi-exponentially with an initial and a terminal half-life of 21 min and 1.7h respectively.
Lastest Price from Atosiban manufacturers
  • Atosiban
  • US $10.00 /kg
  • CAS:90779-69-4
  • Min. Order: 1kg
  • Purity: 99%
  • Supply Ability: 1000kg
  • 2024-03-26
  • Atosiban
  • US $220.00-210.00/kilograms
  • CAS:90779-69-4
  • Min. Order: 1kilograms
  • Purity: 99%
  • Supply Ability: 500tons
  • 2024-03-01

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  • Company Name:Hangzhou Peptide Biochem Co.,Ltd
  • Tel:0571-89197072; 18668118770
  • Products Intro:Product Name:Atosiban Impurtiy
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    Purity:95%,98%,99% Package:10mg;25mg;50mg;100mg;1g;10g More...
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  • Company Name:Twochem Co.Ltd.
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  • Company Name:Hangzhou Peptidego Biotech Co.,Ltd.
  • Tel:0571-87213919
  • Products Intro:Product Name:ATOSIBAN Impurities
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    Purity:98% Package:1mg;5mg;10mg;50mg;100mg,1g or according to customer's detail requirement. More...
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  • Company Name:Shaoxing Junyu Biotechnology Co., LTD
  • Tel:0571-88211921 15572296305
  • Products Intro:Product Name:Atosiban Acetate
    CAS:90779-69-4
    Purity:99% HPLC MS Package:1mg;5mg;10mg;100mg;500mg;1kg;5kg;25kg
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  • Company Name:Nanjing Yuye Biotechnology Co., Ltd.
  • Tel: 17826523762
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    Purity:98% Package:1g
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  • Company Name:Shenzhen JYMed Technology Co., Ltd.
  • Tel:755-755-26612112 15013529272;
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    Purity:98% Package:1G/1.00; Remarks:500g More...
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  • Company Name:Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
  • Tel:18014456767 18014456767
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    Purity:>=95% or 98% Package:1mg\g\kg;1mg\g\kg;1mg\g\kg Remarks:g
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