Atosiban
90779-69-4 Basic informationMore
- Product Name:Atosiban
- Synonyms: 1-deamino-2d-tyr-(oet)-4-thr-8-orn-oxytocin oxytocin,1-(3-mercaptopropanoicacid)-2-(o-ethyl-d-tyrosine)-4-l-threonine-8-l rwj22164 1-(3-Mercaptopropionic acid)-2-(3-(p-ethoxyphenyl)-D-alanine)-4-L-thre onine-8-L-ornithineoxytocin [Mpr-D-Tyr(OEt)-Ile-Thr-Asn-Cys]-Pro-Orn-Gly-NH2 (2S)-N-[(1S)-4-Amino-1-(carbamoylmethylcarbamoyl)butyl]-1-[(4S,7S,13S,16R)-13-[(2S)-butan-2-yl]-7-(carbamoylmethyl)-16-[(4-ethoxyphenyl)methyl]-10-(1-hydroxyethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carbonyl]pyrrolidine-2-carboxamide 1-(3-Mercaptopropanoic acid)-2-(O-ethyl-D-tyrosine)-4-L-threonine-8-L-ornithineoxytocin 1-Deamino-2-D-Tyr-(O-ethyl)-4-Thr-8-ornoxytocin
- CAS:90779-69-4
- MF:C43H67N11O12S2
- MW:994.19
- EINECS:806-815-5
- Mol File:90779-69-4.mol
USE
Atosiban was introduced in the UK as an injectable inhibitor of preterm labor, a major
cause of infant morbidity and mortality. This peptidic oxytocin analog is an antagonist of
the vasopressin V<sub>1a</sub> receptor and of the oxytocin receptor which is found in dramatically
increased concentration in the uterine myometrium of pregnant women near term. It
competitively inhibited contractions in the pregnant guinea pig uterus induced by oxytocin
and vasopressin. In a multicenter, double-blind, placebo-controlled trial, treatment with
atosiban caused pregnancy prolongation for up to 7 days in women with more than 28
weeks of gestation. In a comparative clinical trial, atosiban showed a comparable tocolytic
action (uterine relaxant) to ritodrine but the former was significantly better tolerated,
especially with regards to maternal cardiovascular side effects. In healthy volunteers,
plasma levels of atosiban decreased bi-exponentially with an initial and a terminal half-life of 21 min and 1.7h respectively.
Lastest Price from Atosiban manufacturers
- Atosiban
- US $0.00-0.00/BOX
- CAS:90779-69-4
- Min. Order: 1BOX
- Purity: 99.99%
- Supply Ability: 1000
- 2024-11-27
- Atosiban
- US $500.00-300.00/kg
- CAS:90779-69-4
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000
- 2024-11-27
Browse by Nationality 90779-69-4 Suppliers >Global suppliers
Beijing (11) Shanghai (74) Chongqing (2) Sichuan (12) Guangdong (17) Zhejiang (32) Fujian (6) Hunan (1) Hubei (65) Shandong (9) Shanxi (1) Henan (10) Hebei (9) Liaoning (1) Anhui (11) Jiangsu (36) Jiangxi (5) Shaanxi (9) Hong Kong (2) Other (2) Member (289) All (315)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Hangzhou Peptide Biochem Co.,Ltd
- Tel:0571-89197072; 18668118770
- Products Intro:Product Name:Atosiban Impurtiy
CAS:90779-69-4
Purity:95%,98%,99% Package:10mg;25mg;50mg;100mg;1g;10g More... - CB Index:56
- Related Information:Catalog(248)
- Company Name:Hangzhou Peptidego Biotech Co.,Ltd.
- Tel:0571-87213919
- Products Intro:Product Name:ATOSIBAN Impurities
CAS:90779-69-4
Purity:98% Package:1mg;5mg;10mg;50mg;100mg,1g or according to customer's detail requirement. More... - CB Index:58
- Related Information:Catalog(6756)
- Company Name:Shaoxing Junyu Biotechnology Co., LTD
- Tel:0571-88211921 15572296305
- Products Intro:Product Name:Atosiban Acetate
CAS:90779-69-4
Purity:99% HPLC MS Package:1mg;5mg;10mg;100mg;500mg;1kg;5kg;25kg - CB Index:58
- Related Information:Catalog(5128)
- Company Name:Shenzhen JYMed Technology Co., Ltd.
- Tel:755-755-26612112 15013529272;
- Products Intro:Product Name:Atosiban; Atosiban Acetate
CAS:90779-69-4
Purity:98% Package:1G/1.00; Remarks:500g More... - CB Index:58
- Related Information:Catalog(81)
- Company Name:Zhongke Huayao (Jiangsu) Biotechnology Co., Ltd
- Tel: 18014456767
- Products Intro:Product Name:Atosiban
CAS:90779-69-4
Purity:≥95% or 98% Package:1mg\g\kg;1mg\g\kg;1mg\g\kg - CB Index:58
- Related Information:Catalog(1350)
- Company Name:Beijing Zhongshuo Pharmaceutical Technology Development Co., Ltd
- Tel:010-53679529 13801208576
- Products Intro:Product Name:Atosiban Acetate
CAS:90779-69-4
Purity:99% HPLC Package:25G,100G - CB Index:65
- Related Information:Catalog(99)
- Company Name:Suzhou Tianma Pharma Group Tianji Bio-Pharmaceutical Co., Ltd.
- Tel:0512-68322275 15850786624
- Products Intro:Product Name:Atosiban Acetate
CAS:90779-69-4
Purity:98% Package:G - CB Index:58
- Related Information:Catalog(30)