Acrivastine

• Product Name:Acrivastine
• Synonyms: (e)-3-[6-[(e)-1-(4-methylphenyl)-3-pyrrolidin-1-ylprop-1-enyl]pyridin-2-yl]prop-2-enoic acid ACRIVASTINE Acrivastin (E，E)-3-[6-[1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-2-pyridinyl]-2-propenoic acid BW-270C BW-825C BW-A825C (E)-3-[6-[(E)-1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl]-2-pyridinyl]propenoic acid
• CAS:87848-99-5
• MF:C22H24N2O2
• MW:348.44
• EINECS:
• Mol File:87848-99-5.mol
• 

Acrivastine, (E, E)-3-[6-[1-(4-methylphenyl)-3-(1-pyrrolidinyl)-1-propenyl-2-pyridinyl]-2-propenoic acid(Semprex), is a fixed-combination product of the antihistamineacrivastine (8 mg) with the decongestant pseudoephedrine(60 mg). Acrivastine is an odorless, white to pale cream crystallinepowder that is soluble in chloroform and alcohol andslightly soluble in water.<br/>Acrivastine is an analog of triprolidine containing acarboxyethenyl moiety at the 6-position of the pyridylring. Acrivastine shows antihistaminic potency and durationof action comparable to those of triprolidine (Table23.2). Unlike triprolidine, acrivastine does not display significantanticholinergic activity at therapeutic concentrations.Also, the enhanced polarity of this compound resultingfrom carboxyethenyl substitution limits BBBaccumulation, and thus, this compound produces less sedationthan triprolidine.<br/>Limited pharmacokinetic data are available for this compound.Orally administered drug has a half-life of about 1.7hours and a total body clearance of 4.4 mL/min per kilogram.The mean peak plasma concentrations are reported tovary widely, and the drug appears to penetrate the CNSpoorly. The metabolic fate of acrivastine has not beenreported.

• Acrivastine
• 
• US $1.00-1.00/KG
• CAS:87848-99-5
• Min. Order: 1g
• Purity: 99%
• Supply Ability: 50tons
• 2025-01-03

• Acrivastine
• 
• US $15.00-10.00/KG
• CAS:87848-99-5
• Min. Order: 1KG
• Purity: 99%+ HPLC
• Supply Ability: Monthly supply of 1 ton
• 2021-07-13

• Company Name:Career Henan Chemica Co
• Tel:+86-0371-86658258
• Products Intro:Product Name:Acrivastine
  CAS:87848-99-5
  Purity:0.99summer Package:5KG;1KG Remarks:Summer 618
• CB Index:58
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• Company Name:Shaanxi Dideu Medichem Co. Ltd
• Tel:+86-029-89586680
• Products Intro:Product Name:Acrivastine USP/EP/BP
  CAS:87848-99-5
  Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
• CB Index:58
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• Company Name:AFINE CHEMICALS LIMITED
• Tel:+86-0571-85134551
• Products Intro:Product Name:ACRIVASTINE
  CAS:87848-99-5
  Purity:98%+ Package:Standard or custom package Remarks:excellent quality and reliable supplier
• CB Index:58
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• Company Name:Finetech Industry Limited
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• Products Intro:Product Name:(2E)-3-{6-[(1E)-1-(4-Methylphenyl)-3-(1-pyrrolidinyl)-1-propen-1-yl]-2-pyridinyl}acrylic acid
  CAS:87848-99-5
  Purity:98% Package:1g,10g,25g,100g,500g,1kg
• CB Index:58
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• Company Name:Baoji Guokang Healthchem Co., Ltd.
• Tel:+86-0917-3909592
• Products Intro:Product Name:Acrivastine
  CAS:87848-99-5
  Purity:0.99 Package:1KG
• CB Index:58
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• Company Name:Dayang Chem (Hangzhou) Co.,Ltd.
• Tel:+86-0571-88938639
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  CAS:87848-99-5
  Purity:0.95&0.99 Package:0.1KG;1KG;1000KG Remarks:Hot sales
• CB Index:58
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• Company Name:Hefei TNJ Chemical Industry Co.,Ltd.
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  CAS:87848-99-5
  
• CB Index:58
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• Company Name:Amadis Chemical Company Limited
• Tel:571-89925085
• Products Intro:Product Name:Acrivastine
  CAS:87848-99-5
  Purity:0.97 Package:mgs,gs,kgs Remarks:A916142
• CB Index:58
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