Brentuximab
914088-09-8 Basic informationMore
- Product Name:Brentuximab
- Synonyms: Brentuximab Brentuximab Vedotin Moxetumomab Anti-CLDN18.2 Anti NS1 of dengue virus Research Grade Brentuximab(DHD80901) Adcetris cAC10-vcMMAE
- CAS:914088-09-8
- MF:
- MW:0
- EINECS:
- Mol File:Mol File
-
USE
Brentuximab verdotin was approved by the U.S. FDA in August 2011
for treatment of Hodgkin’s lymphoma (HL) in patients who have failed autologous stem cell transplant (ASCT) or ASCT ineligible patients who have
failed at least two prior chemotherapy regimens, and for second line treatment of systemic anaplastic large cell leukemia (ALCL).
Brentuximab verdotin is a chimeric (mouse V region/human
C region) CD30 binding monoclonal antibody (cAC10) that is
conjugated via cysteine residues to a small molecule comprising a cysteine
reactive dipeptide linker moiety and the microtubule polymerization
inhibitor monomethyl auristatin E(MMAE). The antibody component
of the drug binds to CD30 expressing tumor cells, and the active
cytotoxic component, MMAE, is released by proteolytic cleavage of the
dipeptide linker moiety.
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Brentuximab
CAS:914088-09-8
Purity:95% Package:2mg;5mg;10mg More... - CB Index:58
- Related Information:Catalog(9806)
- Company Name:ShangHai Biochempartner Co.,Ltd
- Tel:177-54423994 17754423994
- Products Intro:Product Name:Brentuximab Vedotin
CAS:914088-09-8
Purity:95% Package:100ug;500ug;1mg - CB Index:62
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- Company Name:Guangzhou Hongyuan Chemical Co.,Ltd
- Tel: 15817493340
- Products Intro:Product Name:Brentuximab vedotin
CAS:914088-09-8
Purity:95% - CB Index:58
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- Company Name:Wuhan Chemstan Biotechnology Co., Ltd.
- Tel:027-65317797 15926423062
- Products Intro:Product Name:Brentuximab Vedotin
CAS:914088-09-8
Purity:>95% Package:100ug;200ug;1mg - CB Index:58
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- Company Name:TargetMol Chemicals Inc.
- Tel: 4008200310
- Products Intro:Product Name:Brentuximab vedotin
CAS:914088-09-8
Purity:97.73% (SEC-HPLC) Package:5mg/RMB 8980;1mg/RMB 4130;25mg/RMB 17900 - CB Index:58
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- Company Name:Biolab Reagents
- Tel:027-65279366 18162686757
- Products Intro:Product Name:Brentuximab
CAS:914088-09-8
Purity:PAGE:>95% Package:1支;1支;1支 - CB Index:58
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- Company Name:Hubei Qingbei Yunyan Pharmaceutical Technology Co., Ltd
- Tel:18162595016; 18162595016
- Products Intro:Product Name:Esperamicin P
CAS:914088-09-8
Purity:95%+HPLC Package:10mg;25mg;50mg;100mg;200mg - CB Index:58
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- Company Name:Shanghai jerryxing Biomedical Technology Co., Ltd
- Tel: 17721492509
- Products Intro:Product Name:Brentuximab
CAS:914088-09-8
Purity:98% HPLC Package:500mg;1g;10g;100g;1kg - CB Index:58
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