KIGAMICIN C
680571-51-1 Basic informationMore
- Product Name:KIGAMICIN C
- Synonyms: KIGAMICIN C Oxazolo[3,2-b]xantheno[4',3',2':4,5][1,3]benzodioxino[7,6-g]isoquinoline-16,19-dione, 3-[[(2S,5S,6R)-5-[(2,6-dideoxy-3-O-methyl-β-D-arabino-hexopyranosyl)oxy]tetrahydro-6-methyl-2H-pyran-2-yl]oxy]-1,2,3,4,8a,9,11,11a,13,14-decahydro-1,4,17,18-tetrahydroxy-11a-methyl-, (1S,3R,4S,8aR,11aR)-
- CAS:680571-51-1
- MF:C41H47NO16
- MW:809.81
- EINECS:
- Mol File:680571-51-1.mol
-
USE
Kigamicin C was discovered by an anti-austerity strategy, targeting cancer cells' tolerance to starvation. It selectively kills PANC-1 cells (a pancreatic cell line) at concentrations 100 times lower under nutrient starved conditions than in normal conditions. The mechanism of action is proposed to be via blockade of aPKB/Akt activation, caused by the withdrawal of nutrients. It is active in vivo against a human pancreatic cancer xenograft model. Kigamicin C also inhibits the growth of Gram positive bacteria including MRSA, but is not active against Gram negative bacteria.
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Kigamicin C
CAS:680571-51-1
Purity:97% Package:0.5mg;2.5mg More... - CB Index:58
- Related Information:Catalog(9806)
- Company Name:Lynnchem
- Tel:86-(0)29-85992781 17792393971
- Products Intro:Product Name:KIGAMICIN C
CAS:680571-51-1
Purity:>98% by HPLC Package:1mg;5mg More... - CB Index:58
- Related Information:Catalog(4587)
- Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel:+86-400-002-6226 +86-13028896684;
- Products Intro:Product Name:Kigamicin C
CAS:680571-51-1
More... - CB Index:58
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- Company Name:ChemeGen(Shanghai) Biotechnology Co.,Ltd.
- Tel: 18818260767
- Products Intro:Product Name:Kigamicin C
CAS:680571-51-1
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g - CB Index:58
- Related Information:Catalog(11218)
- Company Name:Zhejiang Huida Biotech Co., LTD
- Tel:0571-89903882 13626641628
- Products Intro:Product Name:Kigamicin C
CAS:680571-51-1
Purity:99% HPLC Package:10mg；100mg；1g；10g；100g - CB Index:58
- Related Information:Catalog(3656)
- Company Name:MedBioPharmaceutical Technology Inc
- Tel:021-69568360 18916172912
- Products Intro:Product Name:KIGAMICIN C
CAS:680571-51-1
Purity:98% Package:500ug; 2.5mg Remarks:Medbio - CB Index:58
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