Mizolastine
108612-45-9 Basic informationMore
- Product Name:Mizolastine
- Synonyms: 4(1h)-pyrimidinone,2-((1-(1-((4-fluorophenyl)methyl)-1h-benzimidazol-2-yl)-4-p iperidinyl)methylamino)- 2-[[1-[1-[(4-fluorophenyl)methyl]benzoimidazol-2-yl]-4-piperidyl]-methyl-amino]-3h-pyrimidin-4-one MIZOLASTINE 2-[[1-[1-[(4-fluorophenyl)methyl]-1H-benzimidazol-2-yl]-4-piperidinyl]methylamino]-4(1H)-pyrimidinone Mizolastine HCl 2-[[1-[1-(4-fluorobenzyl)benzimidazol-2-yl]-4-piperidyl]-methyl-amino]-1H-pyrimidin-6-one 2-[[1-[1-[(4-fluorophenyl)methyl]benzimidazol-2-yl]piperidin-4-yl]-methyl-amino]-1H-pyrimidin-6-one
- CAS:108612-45-9
- MF:C24H25FN6O
- MW:432.49
- EINECS:1308068-626-2
- Mol File:108612-45-9.mol
USE
Mizolastine was marketed in Germany and Switzerland as Mizollen for
the symptomatic relief of seasonal and perennial allergic rhinoconjunctivitis and
urticaria. Mizolastine is a new long-acting, orally active antihistaminic agent with
a rapid onset of action ; the two most recent H1 antagonists launched were
fexofenadine, metabolite of terfenadine (Sepracor, 1996) and Olopatadine
(Kyowa Hakko, 1997). Mizolastine can be prepared in 2 steps from 2-chloro 1-
(4-fluorobenzyl)benzimidazole by successive condensations of appropriate
amine and thioether. Mizolastine selectively blocks the peripheral H1 receptors
(but not the serotonergic, noradrenergic, muscarinic receptors) with a minimal
occupancy of brain receptors, and therefore does not elicit any sedative effects.
Moreover, Mizolastine does not produce cardiac rhythm disorders which have
been associated with certain non-sedating antihistamines in humans.
Lastest Price from Mizolastine manufacturers
- Mizolastine
- US $0.00 /kg
- CAS:108612-45-9
- Min. Order: 1kg
- Purity: 98.0 ~ 102%
- Supply Ability: 20tons
- 2024-10-25
- Mizolastine
- US $100.00 /kg
- CAS:108612-45-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 1000tons
- 2023-09-07
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- Company Name:Beijing Jialin Pharmaceutical Co., Ltd.
- Tel:010-85392752
- Products Intro:CAS:108612-45-9
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Mizolastine, 98%
CAS:108612-45-9
Purity:98% Package:1G;5G More... - CB Index:76
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- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
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Purity:98.0% LC&T Package:1G,5G More... - CB Index:81
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- Company Name:Adamas Reagent, Ltd.
- Tel:400-6009262 16621234537
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Purity:对照品 Package:10mg~500mg Remarks:AC001419000 - CB Index:59
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- Company Name:Shanghai Sunway Pharmaceutical Technology Co., Ltd
- Tel:021-51613915-820 13611835272
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CAS:108612-45-9
Purity:95% Package:5g; 50g;100g;1kg;10kg More... - CB Index:57
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- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
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Purity:>98.5%,BR Package:100MG Remarks:1380 More... - CB Index:58
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