Pimecrolimus
137071-32-0 Basic informationMore
- Product Name:Pimecrolimus
- Synonyms: ASM 981 SDZ-ASM 981 Picrolimus Pimecrolimus 15,19-Epoxy-3H-pyrido(2,1-C)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 3-((1E)-2-((1R,3R,4S)-4-chloro-3-methoxycyclohexyl)-1-methylethenyl)-8-ethyl-5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S,4R,5S,8R,9E,12S,14S,15R,16S,18R,19R,26as)- 15,19-Epoxy-3H-pyrido(2,1-C)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 3-(2-(4-chloro-3-methoxycyclohexyl)-1-methylethenyl)-8-ethyl-, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26A-hexadecahydro-5,19-dihydroxy-14,16-dimethoxy-4,10,12,18-tetramethyl-, (3S-(3R*(E(1S*,3S*,4R*)),4S*,5R*,8S*,9E,12R*,14R*,15S*,16R*,18S*,19S*,26ar*))- Unii-7kyv510875 PiMecroliMus(Elidel, SDZ-ASM-981)
- CAS:137071-32-0
- MF:C43H68ClNO11
- MW:810.45
- EINECS:603-999-7
- Mol File:137071-32-0.mol
-
USE
Pimecrolimus is a semi-synthetic, macrocyclic lactone derived from ascomycin by activation of the 32-hydroxy group with a triflate ester, and nucleophilic substitution with chloride under phase transfer conditions to provide the chloro analogue. Pimecrolimus has been targeted for treatment of inflammatory skin disorders. Like all tacrolimus analogues, pimecrolimus binds to receptor protein, FKBP12. The complex then binds to mTOR preventing it from interacting with target proteins.
Lastest Price from Pimecrolimus manufacturers
- Pimecrolimus
-
- US $0.00 /KG
- CAS:137071-32-0
- Min. Order: 100g
- Purity: 98%+
- Supply Ability: 100kg
- 2024-03-16
- Pimecrolimus
-
- US $0.00 /KG
- CAS:137071-32-0
- Min. Order: 100g
- Purity: 98%+
- Supply Ability: 100kg
- 2024-03-16
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- Company Name:Shanghai Arbor Chemical Co., Ltd.
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- Products Intro:Product Name:Pimecrolimus
CAS:137071-32-0
Purity:98% Package:10G 100G 1KG More... - CB Index:55
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