Dabigatran etexilate
211915-06-9 Basic informationMore
- Product Name:Dabigatran etexilate
- Synonyms: Pradaxa (dabigatran) Dabigatran Etexilate (free base) Alanine, N-[[2-[[[4-[[[(hexyloxy)carbonyl]aMino]iMinoMethyl]phenyl]aMino]Methyl]-1-Methyl-1H-benziMidazol-5-yl]carbonyl]-N-2-pyridinyl-, ethyl ester BIBR-1048(Dabigatran etexilate) BIBR 1048 Prazaxa (E)-ethyl 3-(2-((4-(N'-(hexyloxycarbonyl)carbamimidoyl)phenylamino)methyl)-1-methyl-N-(pyridin-2-yl)-1H-benzo[d]imidazole-5-carboxamido)propanoate BIBR-1048, >=99%
- CAS:211915-06-9
- MF:C34H41N7O5
- MW:627.73
- EINECS:606-722-8
- Mol File:211915-06-9.mol
USE
Dabigatran etexilate is an orally administered pro-drug of dabigatran,
which is a direct inhibitor of thrombin and a potent anticoagulant. The serine protease thrombin is the final mediator in the coagulation cascade
that leads to the production of fibrin, the main protein component of
blood clots. Thrombin is also a potent activator of platelets. Consequently, thrombin inhibitors have found utility as anticoagulants in
treating arterial and venous thrombosis.
Warfarin, although orally available, has a
narrow therapeutic index and requires frequent monitoring and dosage
adjustment. Low-molecular-weight heparins provide better safety profile
and less inter-patient variability; however, these agents are only available
for parenteral administration. Direct thrombin inhibitors (DTIs) are a
new class of anticoagulants that act by directly binding to thrombin at its
catalytic or fibrinogen-binding sites, or both. Unlike the heparins, DTIs do not require the activation of secondary factors such as antithrombin to derive their activity, which makes their action more predictable. In addition, their ability to inhibit both free and clot-bound thrombin predisposes them for enhanced anticoagulation effect.
Lastest Price from Dabigatran etexilate manufacturers
- Dabigatran Etexilate
- US $0.00 /Kg/Bag
- CAS:211915-06-9
- Min. Order: 2Kg/Bag
- Purity: 99% up, High Density
- Supply Ability: 20 tons
- 2024-12-18
- Dabigatran etexilate
- US $500.00-300.00/kg
- CAS:211915-06-9
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000
- 2024-12-18
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- Company Name:Kaifeng Mingren Pharmaceutical Co.,LTD
- Tel:0371-65741762
- Products Intro:Product Name:Dabigatran etexilate
CAS:211915-06-9
Purity:98% Package:10mg - CB Index:58
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- Company Name:Guangzhou Dreampharm Biotechnology Co., Ltd.
- Tel:020-36607679 17825480238
- Products Intro:Product Name:dabigatran
CAS:211915-06-9
Purity:98% HPLC Package:25mg,50mg,100mg - CB Index:12
- Related Information:Catalog(9919)
- Company Name:Nanjing Shanyao Kangcheng biomedical Co., Ltd.
- Tel: 15722982350
- Products Intro:Product Name:Dabigatran etexilate
CAS:211915-06-9
Purity:99%+ Package:1kg;10kg - CB Index:58
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
- Products Intro:Product Name:Dabigatran etexilate
CAS:211915-06-9
Remarks:C13523 More... - CB Index:61
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- Company Name:Beijing HwrkChemical Technology Co., Ltd
- Tel:010-89508211 18501085097
- Products Intro:Product Name:dabigatran etexilate
CAS:211915-06-9
Purity:0.00% Package:1g - CB Index:55
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- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:Dabigatran etexilate
CAS:211915-06-9
Purity:97% Package:1g;5g;100mg;250mg;2.5g;500mg;1EA;20mg Remarks:NULL More... - CB Index:61
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- Company Name:Jia Xing Isenchem Co.,Ltd
- Tel:0573-85285100 18627885956
- Products Intro:CAS:211915-06-9
Purity:98% (HPLC or GC) Package:25g,100g,500g;1kg More... - CB Index:66
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