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361442-04-8

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361442-04-8 Basic informationMore
USE
Saxagliptin (rINN), previously identified as BMS-477118, is an oral hypoglycemic (anti-diabetic drug) of the dipeptidyl peptidase-4 (DPP-4) inhibitor class of drugs. Early development was solely by Bristol-Myers Squibb; in 2007 AstraZeneca joined with Bristol-Myers Squibb to co-develop the final compound and collaborate on the marketing of the drug. In June 2008, it was announced that Onglyza would be the trade name under which saxagliptin will be marketed.<br /> In April 2016, the U.S. FDA added a warning about increased risk of heart failure.This was based on data in an article that concluded &quot;DPP-4 inhibition with saxagliptin did not increase or decrease the rate of ischemic events, though the rate of hospitalization for heart failure was increased. Although saxagliptin improves glycemic control, other approaches are necessary to reduce cardiovascular risk in patients with diabetes.&quot;<br /> Saxagliptin is used as monotherapy or in combination with other drugs for the treatment of type 2 diabetes. There is no evidence to decrease the risk of heart attacks or strokes.It increases the risk of hospitalization for heart failure by about 27%. Like other DPP-4 inhibitors, it has relatively modest HbA1c lowering ability, is associated with a relatively modest risk of hypoglycemia, and does not cause weight gain.
Lastest Price from Saxagliptin manufacturers
  • Saxagliptin
  • US $0.00-0.00/KG
  • CAS:361442-04-8
  • Min. Order: 1KG
  • Purity: 99.0%
  • Supply Ability: 500 MT
  • 2020-05-12
  • Saxagliptin
  • US $1.00 /KG
  • CAS:361442-04-8
  • Min. Order: 1KG
  • Purity: 99%
  • Supply Ability: 200kgs
  • 2020-03-06

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  • Company Name:Hefei QiChang Biological Technology Co., Ltd.
  • Tel:17756579152
  • Products Intro:Product Name:Saxagliptin
    CAS:361442-04-8
    Purity:99% Package:100g/20000
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  • Company Name:Chembest Research Laboratories Limited
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