Cidofovir
113852-37-2 Basic informationMore
- Product Name:Cidofovir
- Synonyms: Cidofovir (Vistide) (S)-[1-(4-AMino-2-oxo-pyriMidin-1(2H)-yl)-3-hydroxy-propan-2-yl]oxyMethylphosphonic acid ({[(S)-1-(4-amino-2-oxo-1,2-dihydropyrimidin-1-yl)-3-hydroxypropan-2-yl]oxy}methyl)phosphonic acid Cidofovir(GS-504) (S)-(3-(4-amino-2-oxopyrimidin-1(2H)-yl)-1-hydroxypropan-2-yloxy)methylphosphonic acid (S)-1-[3-HYDROXY-2-(PHOSPHONYL-METHOXY)PROPYL]-CYTOSINE (S)-1-(3-HYDROXY-2-PHOSPHONYLMETHOXYPROYPL)CYTOSINE [1-(4-amino-2-oxo-pyrimidin-1-yl)-3-hydroxy-propan-2-yl]oxymethylphosphonic acid
- CAS:113852-37-2
- MF:C8H14N3O6P
- MW:279.19
- EINECS:638-807-0
- Mol File:113852-37-2.mol
USE
Cidofovir, (S)-3-hydroxy-2-phosphonomethoxypropyl cytosine(HPMPC, Vistide), is an acyclonucleotide analog thatpossesses broad-spectrum activity against several DNAviruses. Unlike other nucleotide analogs that are activated tonucleoside phosphates, Cidofovir is a phosphonic acid derivative.The phosphonic acid is not hydrolyzed by phosphatasesin vivo but is phosphorylated by cellular kinases to yield adiphosphate. The diphosphate acts as an antimetabolite to deoxycytosinetriphosphate (dCTP). Cidofovir diphosphate is acompetitive inhibitor of viral DNA polymerase and can beincorporated into the growing viral DNA strand, causingDNA chain termination.<br/>Cidofovir possesses a high therapeutic index against CMVand has been approved for treating CMV retinitis in patientswith AIDS. Cidofovir is administered by slow, constant intravenousinfusion in a dose of 5 mg/kg over a 1-hour periodonce a week for 2 weeks. This treatment is followed by amaintenance dose every 2 weeks.
Lastest Price from Cidofovir manufacturers
- Cidofovir Anhydrous
- US $0.00-0.00/G
- CAS:113852-37-2
- Min. Order: 10G
- Purity: 99%
- Supply Ability: 10KG
- 2024-12-20
- Cidofovir
- US $0.00 /g
- CAS:113852-37-2
- Min. Order: 1g
- Purity: More Than 99%
- Supply Ability: 50kg/Month
- 2024-11-18
Browse by Nationality 113852-37-2 Suppliers >Global suppliers
Beijing (14) Shanghai (61) Tianjin (4) Chongqing (3) Sichuan (3) Guangdong (11) Zhejiang (17) Fujian (3) Hunan (1) Hubei (39) Shandong (7) Shanxi (1) Henan (9) Hebei (3) Liaoning (1) Anhui (8) Jiangsu (23) Jiangxi (4) Shaanxi (4) Hong Kong (3) Other (1) Member (213) All (220)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Tianjin Keluo Pharmaceutical Technology Co. LTD
- Tel:022-23869539 18920052327
- Products Intro:CAS:113852-37-2
Purity:99 Package:100克/RMB 500;10克 - CB Index:58
- Related Information:Catalog(62)
- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
- Products Intro:Product Name:Cidofovir anhydrous
CAS:113852-37-2
Remarks:C13472 More... - CB Index:61
- Related Information:Catalog(6005)
- Company Name:Innochem(Beijing) Technology Co.,Ltd.
- Tel:10-56541685 13070143590
- Products Intro:Product Name:Cidofovir
CAS:113852-37-2
Purity:99.0% Package:1g;100g;1000g More... - CB Index:57
- Related Information:Catalog(124)
- Company Name:Hunan Hui Bai Shi Biotechnology Co., Ltd.
- Tel:0731-85526065 13308475853
- Products Intro:Product Name:Cidofovir
CAS:113852-37-2
Purity:98% HPLC Package:100g;500g - CB Index:62
- Related Information:Catalog(4554)