Ketotifen fumarate

• Product Name:Ketotifen fumarate
• Synonyms: KETOTIFEN FUMARATE EP Allerkif Anatifen Ketotifen Hydrogen FuMarate, EP 4-(1-Methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9H)-one fuMarate 4,9-Dihydro-4-(1-Methyl-4-piperidinylidene)-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-one (2E)-2-Butenedioate Totifen Zasten
• CAS:34580-14-8
• MF:C23H23NO5S
• MW:425.5
• EINECS:252-100-0
• Mol File:34580-14-8.mol
• 

Ketotifen fumarate is a kind of strong anti-allergic drugs containing simultaneously of both tricyclic structure as well as piperidine structure. It is characterized by both a strong antagonism effect on histamine H1 receptor and inhibitory effect of the release of the mediator of allergic reaction. It can inhibit the release various kinds of mediators of mast cells, basophils and macrophages, including the release of slow reacting substances and other active substances. It also has antagonism effect on the calcium ion; can inhibit the activity of phosphodiesterase; increase the intracellular cAMP level inside mast cells. Moreover, it can also inhibiting the chemotaxis and inflammation of neutrophil with an effect 10 times as strong as that of chlorpheniramine, and it also has a long duration time which is better compared with sodium cromolyn. Ketotifen fumarate has therapeutic effect on both Ⅰ and Ⅲ type of allergic reaction. Its peak blood concentrations can sustain for 2 to 3 hours with a half-life of 22 hours during which 60% goes through urinary excretion, 40% goes through the fecal excretion. Children usually have a faster excretion rate of it than adults. Long-term treatment will not cause resistance. No rebound phenomenon will occur with interruption of treatment.

• Ketotifen fumarate
• 
• US $0.00-0.00/KG
• CAS:34580-14-8
• Min. Order: 1KG
• Purity: 99
• Supply Ability: 10 tons
• 2024-04-24

• Ketotifen fumarate
• 
• US $8.00-6.00/kg
• CAS:34580-14-8
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: g-kg-tons, free sample is available
• 2024-04-23

• Company Name:Hubei kangen Pharmaceutical Chemical Co., Ltd
• Tel:15337215803 15337215803
• Products Intro:Product Name:Ketotifen fumarate
  CAS:34580-14-8
  Purity:99.9%HPLC Package:100g;1kg;10kg;25kg More...
• CB Index:56
• Related Information:Catalog(235)

• Company Name:Jiangxi ravel Biotechnology Co.,Ltd
• Tel:400-880-2824 15608648206
• Products Intro:Product Name:Ketotifen fumarate
  CAS:34580-14-8
  Purity:99% HPLC Package:5KG;1KG
• CB Index:58
• Related Information:Catalog(2608)

• Company Name:Hubei Hengluyuan Technology Co., Ltd.
• Tel:027-88188016 18986219475
• Products Intro:Product Name:ketotifen fumarate
  CAS:34580-14-8
  Purity:99 More...
• CB Index:58
• Related Information:Catalog(576)

• Company Name:J & K SCIENTIFIC LTD.
• Tel:010-82848833 400-666-7788
• Products Intro:Product Name:Ketotifen fumarate salt, 99%, a second-generation noncompetitive H1-antihistamine and mast cell stabilizer
  CAS:34580-14-8
  Purity:99% Package:1G;5G More...
• CB Index:76
• Related Information:Catalog(96815)

• Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
• Tel:4006608290; 18621169109
• Products Intro:Product Name:Ketotifen FuMarate
  CAS:34580-14-8
  Purity:>98.0%(LC)(T) Package:1g;5g Remarks:K0048 More...
• CB Index:62
• Related Information:Catalog(40241)

• Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
• Tel:821-50328103-801 18930552037
• Products Intro:Product Name:Ketotifen fuMarate;4,9-Dihydro-4-(1-Methyl-4-piperidinylidene-10H-benzo[4,5]cyclohepta[1,2-b]thiophen-10-onefuMarate
  CAS:34580-14-8
  Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More...
• CB Index:69
• Related Information:Catalog(15848)