Chloroform
67-66-3 Basic informationMore
- Product Name:Chloroform
- Synonyms: Chloroform 10g [67-66-3] CHLOROFORM, DISTILLED IN GLASS Chloroform Standard Chloroform, stabilized with ethanol, pure Chloroform, stabilized with amylene, for spectroscopy Chloroform, stabilized with ethanol, for analysis Chloroform, ECD tested for pesticide anal., residue <0.0005%, for residue analysis Chloroform, Stabilized, AcroSeal, Extra Dry
- CAS:67-66-3
- MF:CHCl3
- MW:119.38
- EINECS:200-663-8
- Mol File:67-66-3.mol
USE
Chloroform (CHCl3) was first discovered in 1831 by American physician Samuel Guthrie; and independently a few months later by Frenchman Eugène Soubeiran and Justus von Liebig in Germany. Chloroform was named and chemically characterised in 1834 by Jean-Baptiste Dumas. Its anaesthetic properties were noted early in 1847 by Marie-Jean-Pierre Flourens. Unlike ether, chloroform's characteristically sweet odour isn't irritating, although inhalation of concentrated chloroform vapour may cause irritation of exposed mucous surfaces. Chloroform is a more effective anaesthetic than nitrous oxide.<br />
In 1864, the Report of Chloroform Committee of Royal Medical and Chirurgical Society endorsed chloroform as Britain's favourite anaesthetic. But ether was safer for patients.<br />
In 1871, leading anaesthetic manufacturer Edward E. Squibb of Brooklyn estimated [New York Medical Journal (April 1871) 13;389] that of 400,000 administrations of anaesthesia in the USA in 1870, chloroform was the agent used in some 50%, ether for 40%, and other gases and mixtures accounted for the rest.
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