Olodaterol

• Product Name:Olodaterol
• Synonyms: 6-Hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2H-1,4-benzoxazin-3(4H)-one 2H-1,4-Benzoxazin-3(4H)-one, 6-hydroxy-8-[(1R)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]- BI 1744(Olodaterol Striverdi Respimat) Olodaterol Olodaterol ImpurityＡ 　 BI-1744 Striverdi
• CAS:868049-49-4
• MF:C21H26N2O5
• MW:386.44
• EINECS:813-858-3
• Mol File:868049-49-4.mol
• 

In 2013, olodaterol (also known BI-1744 CL) was approved for the treatment of chronic obstructive pulmonary disease (COPD) in Russia (March), Canada (June), and the EuropeanUnion (October). Olodaterol is delivered via the Respimat? Soft Mist? inhaler. Olodaterol was discovered from an effort to identify a β2-adrenergic receptor agonist that could be given once daily and with a superior safety profile over known β2- adrenergic receptor agonists. Olodaterol is a potent β2 agonist (EC₅₀=0.1 nM, intrinsic activity=88%) and is highly selective for the β2 receptor over β1 and β3 receptors. In preclinical models in guinea pigs and dogs, olodaterol had a rapid onset of action and provided bronchoprotection over 24 h. Mechanistic studies indicated that olodaterol forms a highly stable complex with the β2-adrenergic receptor, with a dissociation half-life of 17.8 h. The synthesis of olodaterol proceeds through an (R)-styrene epoxide that is prepared via enantioselective reduction of an α-chloroketone intermediate. Ring opening of the epoxide with 1-(4- methoxyphenyl)-2-methylpropan-2-amine provides olodaterol.

• olodaterol
• 
• US $50.00 /KG
• CAS:868049-49-4
• Min. Order: 1KG
• Purity: 0.99
• Supply Ability: 10000
• 2023-12-11

• Olodaterol
• 
• US $15.00-10.00/KG
• CAS:868049-49-4
• Min. Order: 1KG
• Purity: 99%+ HPLC
• Supply Ability: Monthly supply of 1 ton
• 2021-07-13

• Company Name:Hunan Hui Bai Shi Biotechnology Co., Ltd.
• Tel:0731-85526065 13308475853
• Products Intro:Product Name:Olodaterol
  CAS:868049-49-4
  Purity:98% Package:5mg;10mg
• CB Index:62
• Related Information:Catalog(4550)

• Company Name:Anhui Dexinjia Biopharm Co., Ltd
• Tel:0531-82375878 15269101859
• Products Intro:Product Name:Olodaterol 6-Hydroxy-8-[(1r)-1-hydroxy-2-[[2-(4-methoxyphenyl)-1,1-dimethylethyl]amino]ethyl]-2h-1,4-benzoxazin-3(4h)-one
  CAS:868049-49-4
  Purity:98% Package:25KG;5KG;1KG
• CB Index:58
• Related Information:Catalog(294)

• Company Name:TargetMol Chemicals Inc.
• Tel:021-33632979 15002134094
• Products Intro:Product Name:Lipofectin;Lipofectin
  CAS:868049-49-4
  Package:1 mg;10 mg;2 mg;25 mg;5 mg More...
• CB Index:58
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• Company Name:ShangHai Caerulum Pharma Discovery Co., Ltd.
• Tel: 18149758185
• Products Intro:Product Name:Olodaterol
  CAS:868049-49-4
  Purity:98% Package:10mg;100mg;1g;10g;100g;1kg Remarks:1g More...
• CB Index:58
• Related Information:Catalog(3421)

• Company Name:ChemStrong Scientific Co.,Ltd
• Tel:0755-0755-66853366 13670046396
• Products Intro:Product Name:Olodaterol
  CAS:868049-49-4
  Purity:95% HPLC Package:10mg;25mg;50mg;100mg
• CB Index:56
• Related Information:Catalog(17982)

• Company Name:Shanghai YuLue Chemical Co., Ltd.
• Tel:021-60345187 13671753212
• Products Intro:CAS:868049-49-4
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• CB Index:55
• Related Information:Catalog(10287)