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Nedaplatin

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95734-82-0 Basic informationMore
USE
Nedaplatin, a novel second generation platinum complex, was marketed in Japan for the treatment of a variety of cancers including: head and neck, small-cell and non-small cell lung, oesophageal, prostatic, testicular, ovarian, cervical, bladder, and uterine cancers. Platinum anticancer agents, prototyped by cisplatin, have been reported to be hydrolyzed to the mono- or diaquated species of diamine platinum which react with nucleophilic sites on DNA to cause intrastrand and interstrand crosslinks and DNA-protein crosslinks, which result in cytotoxicity. Nedaplatin was reportedly more active than cisplatin against several solid tumors while sharing less nephro- and gastrointestinal toxicity to cisplatin in viva The minimal renal toxicity displayed by nedaplatin allows its use in patients with deteriorated renal function.
Lastest Price from Nedaplatin manufacturers
  • Nedaplatin
  • US $0.00 /g
  • CAS:95734-82-0
  • Min. Order: 1g
  • Purity: 98%-102%
  • Supply Ability: 100g
  • 2024-11-21
  • Nedaplatin
  • US $15.00-10.00/KG
  • CAS:95734-82-0
  • Min. Order: 1KG
  • Purity: 99%+ HPLC
  • Supply Ability: Monthly supply of 1 ton
  • 2021-07-13

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