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sorivudine

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Sorivudine is an orally-active antiviral nucleoside analog. It has potent and selective activity against herpes simplex virus type-1 (HSV-1) and varicella-zoster virus (VZV). In a cutaneous model infection of mice with HSV-1, oral administration of sorivudine at dose of 20 mg/kg resulted in a significant increase in the survival rate. Five percent sorivudine cream is also useful in the topical treatment of cutaneous HSV-1 infection, including immunocompromised patients. It has been suggested that its antiviral activity may be mediated by inhibition of DNA synthesis in virus infected cells.<br/>Since the metabolite of sorivudine inhibits the enzyme for pyrimidine catabolism, caution should be taken not to use sorivudine in combination with fluorouracil drugs in order to avoid hematological disorders.

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  • Company Name:Shanghai EFE Biological Technology Co., Ltd.
  • Tel:021-65675885 18964387627
  • Products Intro:Product Name:Sorivudine
    CAS:77181-69-2
    Purity:98% Package:1mg;5mg;10mg
  • CB Index:58
  • Related Information:Catalog(9806)
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  • Company Name:Changzhou PBpharmaceutical R&D Co.,Ltd
  • Tel:0519-83990708
  • Products Intro:Product Name:sorivudine
    CAS:77181-69-2
    Purity:95% Package:1g,5g,10g,25g,100g,500g,1kg,5kg,25kg More...
  • CB Index:55
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  • Company Name:Hangzhou Jinghao Biotechnology Co., LTD
  • Tel:17513242016 17513242016
  • Products Intro:Product Name:Sorivudine
    CAS:77181-69-2
    Purity:98% Package:1g;5g;25g;大包装
  • CB Index:58
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  • Company Name:Bide Pharmatech Ltd.
  • Tel:400-1647117 13681763483
  • Products Intro:Product Name:5-((E)-2-Bromovinyl)-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
    CAS:77181-69-2
    Purity:98% Package:10mg;25mg;50mg;100mg;250mg; Remarks:BD151767
  • CB Index:58
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