sorivudine
77181-69-2 Basic informationMore
- Product Name:sorivudine
- Synonyms: sorivudine 1-(β-D-Arabinofuranosyl)-5-[(E)-2-bromoethenyl]uracil 1-β-D-Arabinofuranosyl-5-[(E)-2-bromovinyl]-1,2,3,4-tetrahydropyrimidine-2,4-dione Brovavir BvAraU BV-araU YN-72 Bravavir
- CAS:77181-69-2
- MF:C11H13BrN2O6
- MW:349.13
- EINECS:
- Mol File:77181-69-2.mol
USE
Sorivudine is an orally-active antiviral nucleoside analog. It has potent and selective
activity against herpes simplex virus type-1 (HSV-1) and varicella-zoster virus (VZV). In a
cutaneous model infection of mice with HSV-1, oral administration of sorivudine at dose of
20 mg/kg resulted in a significant increase in the survival rate. Five percent sorivudine cream
is also useful in the topical treatment of cutaneous HSV-1 infection, including
immunocompromised patients. It has been suggested that its antiviral activity may be
mediated by inhibition of DNA synthesis in virus infected cells.<br/>Since the metabolite of sorivudine inhibits the enzyme for pyrimidine catabolism,
caution should be taken not to use sorivudine in combination with fluorouracil drugs in order to
avoid hematological disorders.
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- Company Name:Shanghai EFE Biological Technology Co., Ltd.
- Tel:021-65675885 18964387627
- Products Intro:Product Name:Sorivudine
CAS:77181-69-2
Purity:98% Package:1mg;5mg;10mg - CB Index:58
- Related Information:Catalog(9806)
- Company Name:Changzhou PBpharmaceutical R&D Co.,Ltd
- Tel:0519-83990708
- Products Intro:Product Name:sorivudine
CAS:77181-69-2
Purity:95% Package:1g,5g,10g,25g,100g,500g,1kg,5kg,25kg More... - CB Index:55
- Related Information:Catalog(476)
- Company Name:Hangzhou Jinghao Biotechnology Co., LTD
- Tel:17513242016 17513242016
- Products Intro:Product Name:Sorivudine
CAS:77181-69-2
Purity:98% Package:1g;5g;25g;大包装 - CB Index:58
- Related Information:Catalog(2803)
- Company Name:Bide Pharmatech Ltd.
- Tel:400-1647117 13681763483
- Products Intro:Product Name:5-((E)-2-Bromovinyl)-1-((2R,3S,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
CAS:77181-69-2
Purity:98% Package:10mg;25mg;50mg;100mg;250mg; Remarks:BD151767 - CB Index:58
- Related Information:Catalog(62075)