Trilostane
13647-35-3 Basic informationMore
- Product Name:Trilostane
- Synonyms: TRILOSTANE (2-alpha,4-alpha,5-alpha,17-beta)-4,5-epoxy-17-hydroxy-3-oxoandrostane-2-car 17-beta)-ph (4a,5a,17b)-3,17-Dihydroxy-4,5-epoxyandrost-2-ene-2-carbonitrile 5a-Androstane-2a-carbonitrile, 4a,5-epoxy-17b-hydroxy-3-oxo- Androst-2-ene-2-carbonitrile, 4,5-epoxy-3,17-dihydroxy-, (4a,5a,17b)- 4α,5-Epoxy-3,17β-dihydroxy-5α-androst-2-ene-2-carbonitrile 4α,5-Epoxy-3,17β-dihydroxy-5α-androstan-2-ene-2-carbonitrile
- CAS:13647-35-3
- MF:C20H27NO3
- MW:329.43
- EINECS:237-133-0
- Mol File:13647-35-3.mol
-
USE
Trilostane, that is 4α, 5α-epoxy-2-cyano-3,17β-diol, can reversibly inhibit 3β-hydroxy steroid dehydrogenase and △5, 4-isomerase in the adrenal cortex to block the biosynthesis of mineralocorticoid and glucocorticoid. In 1980, it was approved for the treatment of hyperaldosteronism and cortisol excess disease in the United Kingdom. In 1985, it was approved for the treatment of Cushing's syndrome in the United States, which is adrenal cortex hyperactivity disorder. In view of the older animals, especially older dogs are susceptible to Cushing's syndrome. Trilostane can relieve the disease symptoms of more than 90% of dogs, and improve their quality of life. So the drug has also been granted for the treatment of animals in the United Kingdom. Trilostane itself has no hormonal activity. Its side effects is less, and its safety and tolerability are also particularly good. <br/>
The above information is edited by the chemicalbook of Ge Qian.
Lastest Price from Trilostane manufacturers
- Trilostane
-
- US $0.00 /Kg/Bag
- CAS:13647-35-3
- Min. Order: 2Kg/Bag
- Purity: 99% up, High Density
- Supply Ability: 20 tons
- 2024-12-25
- Trilostane
-
- US $0.00 /g
- CAS:13647-35-3
- Min. Order: 1g
- Purity: More Than 99%
- Supply Ability: 100kg/Month
- 2024-12-25
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- Company Name:Liaoning Pharmaceutical Innovation Co., Ltd
- Tel:+86-02266350830; 16588669988
- Products Intro:Product Name:Trilostane
CAS:13647-35-3
Purity:99% HPLC Package:10g/RMB 100;100g1000g - CB Index:58
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- Company Name:Suzhou Pharmaceutical Technology co.,ltd
- Tel:0510-88771160 18051901298
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- Company Name:Shanghai Linka Biotechnology Co., Ltd.
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Purity:0.99 Package:1G；100G;1KG - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
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- Products Intro:Product Name:Trilostane, 99%
CAS:13647-35-3
Purity:99% Package:1G More... - CB Index:76
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- Company Name:future industrial shanghai co., ltd
- Tel:400-0066400 13621662912
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CAS:13647-35-3
Purity:99% Package:550RMB/ 100mg More... - CB Index:65
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- Company Name:Chembest Research Laboratories Limited
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CAS:13647-35-3
Purity:99% Package:1g;5g;10g;50g;100g;500g;1kg Remarks:C14296 More... - CB Index:61
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