OTX015
202590-98-5 Basic informationMore
- Product Name:OTX015
- Synonyms: OTX015(OTX-015) 6H-Thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide, 4-(4-chlorophenyl)-N-(4-hydroxyphenyl)-2,3,9-trimethyl-, (6S)- MK 8628 MK8628 MK-8628 OTX015;OTX 015;OTX-015 2-((6S)-4-(4-chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepin-6-yl)-N-(4-hydroxyphenyl)acetamide OTX 015
- CAS:202590-98-5
- MF:C25H22ClN5O2S
- MW:491.99
- EINECS:
- Mol File:202590-98-5.mol
-
USE
OTX015 inhibits the binding of BRD2, BRD3, and BRD4 to AcH4 with IC50 ranging from 92 to 112 nM, and inhibits the growth of a variety of human cancer cell lines with GI50 ranging from 60 to 200 nM. OTX015 results in rapid down-regulation of c-MYC expression, and show the synergistic anti-proliferative effects in combination with ALK inhibitors in ALKpos ALCL cell lines.
Lastest Price from OTX015 manufacturers
- OTX015
-
- US $0.00 /mg
- CAS:202590-98-5
- Min. Order: 1mg
- Purity: 98%min
- Supply Ability: 50mg
- 2023-11-15
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- Company Name:Suzhou Hengning Pharmaceutical Technology Co., Ltd.
- Tel:0512-65649061 17365378613
- Products Intro:Product Name:OTX-015
CAS:202590-98-5
More... - CB Index:58
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- Company Name:Shanghai Synchem Pharma Co., ltd
- Tel:021-61984905-1 18016477331
- Products Intro:Product Name:OTX015
CAS:202590-98-5
Purity:98%+ Package:1g/ More... - CB Index:55
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- Company Name:Twochem Co.Ltd
- Tel:021-58111628 15800915896
- Products Intro:Product Name:OTX015
CAS:202590-98-5
Purity:>98% HPLC Package:1g;10g;100g More... - CB Index:55
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- Company Name:Chembest Research Laboratories Limited
- Tel:021-20908456
- Products Intro:Product Name:OTX-015 (MK-8628
CAS:202590-98-5
Purity:98%+ HPLC Package:50mg;100mg;500mg;1g;5g;10g Remarks:Biochemical Reagents; Pharmaceutical Intermediates More... - CB Index:61
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- Company Name:WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd.
- Tel:17702719238 17702719238
- Products Intro:Product Name:OTX-015
CAS:202590-98-5
Purity:98% HPLC Package:50.0mg;100.0mg; 200.0mg;500mg;1g;5g; 10g - CB Index:64
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- Company Name:Shanghai Hanhong Scientific Co.,Ltd.
- Tel:021-54306202 13764082696;
- Products Intro:Product Name:OTX-015
CAS:202590-98-5
Purity:98+% Remarks:AB10548 More... - CB Index:64
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- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:OTX015
CAS:202590-98-5
Purity:>98%,BET bromodomain Package:20MG More... - CB Index:58
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