Rimonabant

• Product Name:Rimonabant
• Synonyms: ACOMPLIA RIMONABANT RIMONABANT(ACOMPLIA,SR141716) 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidinopyrazole-3-carboxamide 1H-Pyrazole-3-carboxamide, 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl- 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide A 281 Sr 141716
• CAS:168273-06-1
• MF:C22H21Cl3N4O
• MW:463.79
• EINECS:200-223-5
• Mol File:168273-06-1.mol
• 

Rimonabant is a first-in-class drug launched as an oral treatment for obesity, and its mechanism of action involves the selective antagonism of cannabinoid type 1 (CB1) receptor. It is specifically indicated as an adjunct to diet and exercise for the treatment of obese patients (body mass index [BMI]≥30 kg/m²), or overweight patients (BMI＞27 kg/m²) with associated risk factors such as type 2 diabetes or dyslipidemia. Additionally, rimonabant is currently under development as a treatment for nicotine dependence. The CB1 and CB2 receptors, along with their endogenous ligands, constitute the endocannabinoid system. The CB1 receptor is expressed in the brain, adipose tissue, and several peripheral organs; the CB2 receptor is predominantly expressed in immune cells. Activation of the CB1 receptor in the CNS is associated with appetite stimulation and the modulation of brain reward mechanism, whereas activation in the periphery favors metabolic processes that lead to hepatic lipogenesis and impaired glucose homeostasis. Rimonabant acts by selectively blocking the action of central and peripheral CB1 receptors, thereby reducing food intake and improving lipid and glucose metabolism.

• Rimonabant
• 
• US $99.00-66.00/kg
• CAS:168273-06-1
• Min. Order: 0.0010000000474974513kg
• Purity: 99%
• Supply Ability: 5000
• 2024-11-23

• Rimonabant
• 
• US $10.00 /kg
• CAS:168273-06-1
• Min. Order: 1kg
• Purity: 99%
• Supply Ability: 10 mt
• 2024-11-11

• Company Name:Chengdu Pengshengyue Pharmaceutical Technology Co. , Ltd.
• Tel:171-5642-2032 19587414261
• Products Intro:Product Name:rimonabant
  CAS:168273-06-1
  
• CB Index:58
• Related Information:Catalog(23)

• Company Name:Chembest Research Laboratories Limited
• Tel:+86-21-20908456
• Products Intro:Product Name:Rimonabant (SR141716)
  CAS:168273-06-1
  Purity:98+% Package:1g;5g;10g Remarks:C14463 More...
• CB Index:61
• Related Information:Catalog(6005)

• Company Name:Beijing HwrkChemical Technology Co., Ltd
• Tel:010-89508211 18501085097
• Products Intro:Product Name:Rimonabant
  CAS:168273-06-1
  Purity:99.00% Package:100g
• CB Index:55
• Related Information:Catalog(8418)

• Company Name:Jia Xing Isenchem Co.,Ltd
• Tel:0573-85285100 18627885956
• Products Intro:CAS:168273-06-1
  Purity:98% (HPLC or GC) Package:25g,100g,500g;241kg More...
• CB Index:66
• Related Information:Catalog(9413)

• Company Name:Shanghai Longsheng chemical Co.,Ltd.
• Tel:021-58099652-8005 13585536065
• Products Intro:CAS:168273-06-1
  Package:9.6g More...
• CB Index:59
• Related Information:Catalog(9809)

• Company Name:Hangzhou Yuhao Chemical Technology Co., Ltd
• Tel:0571-82693216
• Products Intro:Product Name:RiMonabant
  CAS:168273-06-1
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• CB Index:52
• Related Information:Catalog(9387)