Epothilone D
189453-10-9 Basic informationMore
- Product Name:Epothilone D
- Synonyms: Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl-16-(1E)-1-methyl-2-(2-methyl-4-thiazolyl)ethenyl-, (4S,7R,8S,9S,13Z,16S)- Oxacyclohexadec-13-ene-2,6-dione, 4,8-dihydroxy-5,5,7,9,13-pentamethyl -16-(1-methyl-2-(2-methyl-4-thiazolyl)ethenyl)-, (4S-(4R*,7S,8R*,9R*,1 3Z,16R*(E)))- (3S,7S,14S,15S,16R)-3,15-Dihydroxy-2,2,10,14,16-pentamethyl-7-[1-(2-methyl-1,3-thiazol-4-yl)prop-1-en-2-yl]-6-oxacyclohexadec-9-ene-1,5-dione Epothilone D Desoxyepothilone B (4S,7R,8S,9S,13Z,16S)-4,8-Dihydroxy-5,5,7,9,13-pentaMethyl-16-[(1E)-1-Methyl-2-(2-Methyl-4-thiazolyl)ethenyl]oxacyclohexadec-13-ene-2,6-dione 12,13-Desoxyepothilone B Epo D
- CAS:189453-10-9
- MF:C27H41NO5S
- MW:491.68
- EINECS:
- Mol File:189453-10-9.mol
USE
Epothilones are polyketide natural products that inhibit cancer cells by a mechanism similar to paclitaxel, and also are effective against paclitaxel-resistant tumours. Epothilone D is in phase I clinical testing of in patients with advanced solid tumours. Epothilone D is a cytotoxic macrolide that stabilises malignant cells' microtubules and arrests mitosis, a characteristic it shares with other epothilones. They bind to the same hepatic sites as does paclitaxel (Taxol) in a 1:1 stoichiometric ratio of a, b-tubulin heterodimers.
Lastest Price from Epothilone D manufacturers
- Epothilone D
- US $1.10 /g
- CAS:189453-10-9
- Min. Order: 1g
- Purity: 99.9%
- Supply Ability: 100 Tons Min
- 2021-07-03
- Epothilone D
- US $0.00-0.00/Kg
- CAS:189453-10-9
- Min. Order: 1KG
- Purity: 99.0%
- Supply Ability: 800 ton
- 2020-05-03
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- Company Name:Wuhan Yingnuo Pharmaceutical Technology Co., Ltd.
- Tel:+86-027-59232304 15387063101
- Products Intro:Product Name:Epothilone D
CAS:189453-10-9
Purity:98% Package:1KG;100g;1g,100mg - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Epothilone D (synthetic)
CAS:189453-10-9
Package:0.1Mg,1Mg More... - CB Index:76
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
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CAS:189453-10-9
Remarks:C13628 More... - CB Index:61
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- Company Name:Energy Chemical
- Tel:021-021-58432009 400-005-6266
- Products Intro:Product Name:Epothilone D
CAS:189453-10-9
Purity:98% Package:5mg;25mg;100mg;0.1mg;10mg;1mg Remarks:NULL More... - CB Index:61
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- Company Name:Dalian Meilun Biotech Co., Ltd.
- Tel:0411-62910999 13889544652
- Products Intro:Product Name:Epothilone D
CAS:189453-10-9
Purity:>98%,BR Package:5MG Remarks:1600 More... - CB Index:58
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