nifurtimox
23256-30-6 Basic informationMore
- Product Name:nifurtimox
- Synonyms: NIFURIMOX 4-[(5-Nitrofurfurylidene)amino]-3-methylthiomorpholine 1,1-dioxide BAY-2502 Bayer 2502 Bayer-2502 Lampit 3-Methyl-N-[(5-nitro-2-furanyl)methylene]-4-thiomorpholinamine 1,1-dioxide Aids007325
- CAS:23256-30-6
- MF:C10H13N3O5S
- MW:287.29
- EINECS:245-531-0
- Mol File:23256-30-6.mol
-
USE
Nifurtimox is 4-[(5-nitrofurfurylidene) amino]-3-methylthiomorpholine-1,1-dioxide, or Bayer 2502 (Lampit). Theobservation that various derivatives of 5-nitrofuraldehydepossessed, in addition to their antibacterial and antifungal properties, significant and potentially useful antiprotozoalactivity eventually led to discovery of particular nitrofuranswith antitrypanosomal activity.<br/>The most important of such compounds is nifurtimox becauseof its demonstrated effectiveness against T. cruzi, theparasite responsible for South American trypanosomiasis. Infact, use of this drug represents the only clinically proventreatment for both acute and chronic forms of the disease.Nifurtimox is available in the United States from the CDC.Nifurtimox is administered orally. Oral bioavailability ishigh, but considerable first-pass metabolism occurs. Thehalf-life of nifurtimox is 2 to 4 hours. The drug is poorly tolerated,with a high incidence of nausea, vomiting, abdominalpain, and anorexia reported. Symptoms of central andperipheral nervous system toxicity also frequently occurwith nifurtimox.
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- Company Name:Hefei zhongxing Biomedical Co., Ltd.
- Tel: 15955174703
- Products Intro:Product Name:E)-N-(3-methyl-1,1-dioxo-1,4-thiazinan-4-yl)-1-(5-nitrofuran-2-yl)methanimine
CAS:23256-30-6
Purity:99 Package:280g More... - CB Index:58
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:NifurtiMox
CAS:23256-30-6
Package:50Mg,5Mg More... - CB Index:76
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- Company Name:Shanghai Yuanding Chem. Sci. & Tech. Co., Ltd.
- Tel:21-57721279
- Products Intro:Product Name:nifurtimox
CAS:23256-30-6
Purity:97% Package:1g,5g,10g,100g,1kg - CB Index:56
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- Company Name:Shanghai Aladdin Bio-Chem Technology Co.,LTD
- Tel:400-400-6206333 18521732826
- Products Intro:Product Name:Nifurtimox
CAS:23256-30-6
Purity:98% Package:100mg/RMB 8239.90;25mg/RMB 3089.90;50mg/RMB 5149.90 More... - CB Index:65
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- Company Name:Finetech Industry Limited
- Tel:027-87465837 19945049750
- Products Intro:Product Name:Nifurtimox
CAS:23256-30-6
Purity:98% Package:1g;10g;25g;500g;1kg - CB Index:58
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- Company Name:Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
- Tel:025-66113011 18112977050
- Products Intro:Product Name:Nifurtimox
CAS:23256-30-6
Purity:95+% Package:1g;5g;10g - CB Index:50
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