Zolmitriptan
139264-17-8 Basic informationMore
- Product Name:Zolmitriptan
- Synonyms: ZOLMITRIPTANE (4r)-4-[[3-(2-dimethylaminoethyl)-1h-indol-5-yl]methyl]oxazolidin-2-one Zolmitriptan Assists Mi Qu Pu Tanzania Zolmitriptan (150 mg) (4R)-4-({3-[2-(diMethylaMino)ethyl]-1H-indol-5-yl}Methyl)-1,3-oxazolidin-2-one ZolMitriptan(ZoMig) ZolMitriptan API
- CAS:139264-17-8
- MF:C16H21N3O2
- MW:287.36
- EINECS:629-919-0
- Mol File:139264-17-8.mol
USE
Zolmitriptan, the second triptan marketed (approved in1997), has a much better bioavailability (40%–48%) thansumatriptan. It is rapidly absorbed after oral or nasal sprayadministration. It also has an orally disintegrating tablet formulation(Zomig ZMT), which can be taken without water.Zolmitriptan undergoes rapid N-demethylation via CYP1A2to a more potent, active metabolite, N-desmethylzolmitriptan,which is 2 to 6 times more potent than the parentdrug. This active metabolite was detected 5 minutesafter dosing and accounts for about two thirds of the plasmaconcentration of the administered dose of the parent drug.284Thus, it is reasonable to assume that the therapeutic effectsand especially the CNS side effects of zolmitriptan must bein part attributed to the plasma levels of this active metabolite,at least until it is further degraded by hepatic MAO-Ato its inactive indole acetic acid derivatives.
Lastest Price from Zolmitriptan manufacturers
- Zolmitriptan
- US $0.00-0.00/Kg/Bag
- CAS:139264-17-8
- Min. Order: 1Kg/Bag
- Purity: 0.99
- Supply Ability: 20 tons
- 2024-12-20
- Zolmitriptan
- US $120.00 /kg
- CAS:139264-17-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 20ton
- 2024-12-20
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- Company Name:Nanjing Tengyi Biotechnology Co., Ltd
- Tel:025-58851786 17714337195
- Products Intro:Product Name:2-Oxazolidinone, 4-[[3-[2-(dimethylamino)ethyl]-1H-indol-5-yl]methyl]-, (4S)-
CAS:139264-17-8
Purity:98% Package:1g;5g - CB Index:58
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- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:Zolmitriptan, 98%, a selective 5-HT1B/1D/1F receptor agonist
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- Company Name:Chemvon Biotechnology Co., Ltd
- Tel:021-50790412
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Purity:98% Package:1g, 10g, 100g, 200g, 1kg, 5kg More... - CB Index:57
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- Tel:021-20221225 13917446399
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- Company Name:Chembest Research Laboratories Limited
- Tel:+86-21-20908456
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- Company Name:TCI (Shanghai) Development Co., Ltd.
- Tel:021-67121386
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Purity:98.0% LC&T Package:1G,200MG More... - CB Index:81
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