Radotinib
926037-48-1 Basic informationMore
- Product Name:Radotinib
- Synonyms: IY5511 Radotinib Radotinib(IY-5511) 4-Methyl-N-[3-(4-methylimidazol-1-yl)-5-trifluoromethylphenyl]-3-(4-(pyrazin-2-yl)pyrimidin-2-ylamino)benzamide 4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phe... Benzamide, 4-methyl-N-[3-(4-methyl-1H-imidazol-1-yl)-5-(trifluoromethyl)phenyl]-3-[[4-(2-pyrazinyl)-2-pyrimidinyl]amino]- RADOTINIB; IY5511 HCL. IY5511 HCl.
- CAS:926037-48-1
- MF:C27H21F3N8O
- MW:530.5
- EINECS:
- Mol File:926037-48-1.mol
-
USE
Radotinib, an inhibitor of Bcr–Abl tyrosine kinase,was approved in January 2012 in Korea as a second-line treatment for chronic myeloid leukemia (CML).
Radotinib is a TKI with a similar structure to the second-generation TKI, nilotinib, in which a pyridyl group has been replaced with a pyrazinemoiety. The in vitro activity of radotinib against a variety of tumor cell lines is disclosed in an issued patent. Radotinib was significantly more potent than imatinib in all of the cell lines tested. The synthesis of radotinib via amide coupling is described in the patent literature.
Lastest Price from Radotinib manufacturers
Browse by Nationality 926037-48-1 Suppliers >Global suppliers
Beijing (8) Shanghai (39) Chongqing (2) Sichuan (2) Guangdong (14) Zhejiang (9) Hubei (11) Shandong (3) Henan (3) Liaoning (1) Anhui (4) Jiangsu (13) Jiangxi (1) Shaanxi (1) Hong Kong (2) Member (113) All (113)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:ATK CHEMICAL COMPANY LIMITED
- Tel:+undefined-21-51877795
- Products Intro:Product Name:Radotinib;IY5511
CAS:926037-48-1
Purity:98% HPLC Package:5MG;10MG;50MG;100MG,1G,5G More... - CB Index:60
- Related Information:Catalog(33024)
- Company Name:career henan chemical co
- Tel:+86-0371-86658258
- Products Intro:Product Name:Radotinib
CAS:926037-48-1
Purity:>=98% Package:1KG;1USD - CB Index:58
- Related Information:Catalog(29799)
- Company Name:Hubei Ipure Biology Co., Ltd
- Tel:
- Products Intro:Product Name:Radotinib
CAS:926037-48-1
Purity:0.99 Package:5KG;1KG - CB Index:58
- Related Information:Catalog(10237)
- Company Name:HONG KONG IPURE BIOLOGY CO.,LIMITED
- Tel:86 18062405514
- Products Intro:Product Name:Radotinib
CAS:926037-48-1
Purity:.99 Package:5KG;1KG - CB Index:58
- Related Information:Catalog(3461)
- Company Name:Zhejiang J&C Biological Technology Co.,Limited
- Tel:+1-2135480471
- Products Intro:Product Name:Radotinib IY-5511
CAS:926037-48-1
Purity:99% Package:5KG;1KG Remarks:Radotinib IY-5511 - CB Index:58
- Related Information:Catalog(10473)
- Company Name:Hefei TNJ Chemical Industry Co.,Ltd.
- Tel:+86-0551-65418684
- Products Intro:Product Name:4-methyl-N-[3-(4-methylimidazol-1-yl)-5-(trifluoromethyl)phe...
CAS:926037-48-1
- CB Index:58
- Related Information:Catalog(25356)
- Company Name:SHANGHAI KEAN TECHNOLOGY CO., LTD.
- Tel:
- Products Intro:Product Name:4-Methoxy-3-pyridinamine
CAS:926037-48-1
Purity:0.99 Package:100g;1kg;5KG;1KG - CB Index:58
- Related Information:Catalog(40066)
- Company Name:Amadis Chemical Company Limited
- Tel:571-89925085
- Products Intro:Product Name:Radotinib
CAS:926037-48-1
Purity:0.97 Package:mgs,gs,kgs Remarks:A860035 More... - CB Index:58
- Related Information:Catalog(131957)