(E,E)-Bis(2-hydroxybenzylidene)acetone (2-HBA)
131359-24-5 Basic informationMore
- Product Name:(E,E)-Bis(2-hydroxybenzylidene)acetone (2-HBA)
- Synonyms: (E,E)-Bis(2-hydroxybenzylidene)acetone (2-HBA) (1E,4E)-1,5-Bis(2-Hydroxyphenyl)-1,4-pentadien-3-one HBB2 2-HBA (E,E)-Bis(2-hydroxybenzylidene)acetone\n(2-HBA) 2-HBA Exclusive bis(2-hydroxybenzylidene)acetone 1,4-Pentadien-3-one, 1,5-bis(2-hydroxyphenyl)-, (1E,4E)-
- CAS:131359-24-5
- MF:C17H14O3
- MW:266.29
- EINECS:
- Mol File:131359-24-5.mol
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USE
(E,E)-Bis(2-hydroxybenzylidene)acetone (2-HBA) is a synthetic analogue of curcumin that displays strong NAD(P)H:quinone reductase (NQO1) inducer potency in Hepa 1c1c7 cells. 2-HBA, a double Michael reaction acceptor, can directly modify cysteine sulfhydryl groups in Keap1 and consequently suppress Nrf2 ubiquitination which in turn enhances the expression of antioxidative and cytoprotective enzymes. 2-HBA has also been shown to cause G2/M cell cycle arrest and p53-independent, caspase 3-mediated apoptosis.
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- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:(E,E)-Bis(2-hydroxybenzylidene)acetone (2-HBA)
CAS:131359-24-5
Package:250Mg,25Mg More... - CB Index:76
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- Company Name:ShangHai Biochempartner Co.,Ltd
- Tel:177-54423994 17754423994
- Products Intro:Product Name:2-HBA
CAS:131359-24-5
Purity:98% HPLC LCMS Package:100mg;500mg;1g;5g;10g - CB Index:62
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- Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
- Tel:010-60605840 18892239720
- Products Intro:Product Name:2-HBA
CAS:131359-24-5
Purity:98% Package:5mg;10mg;25mg;50mg;100mg - CB Index:58
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- Company Name:MQ (shanghai) Pharmaceuticals Co., Ltd.
- Tel: 13761635123
- Products Intro:Product Name:(E,E)-Bis(2-hydroxybenzylidene)acetone (2-HBA)
CAS:131359-24-5
Purity:＞95% Package:1G,5G More... - CB Index:55
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- Company Name:Angel Pharmatech, Ltd.
- Tel: 17317130613
- Products Intro:Product Name:2-HBA
CAS:131359-24-5
Purity:98% HPLC Package:1G;5G More... - CB Index:58
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- Company Name:Shenzhen Polymeri Biochemical Technology Co., Ltd.
- Tel:+86-400-002-6226 +86-13028896684;
- Products Intro:Product Name:(E,E)-Bis(2-hydroxybenzylidene)acetone (2-HBA)
CAS:131359-24-5
More... - CB Index:58
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