Dabrafenib

• Product Name:Dabrafenib
• Synonyms: Dabrafenib Dabrafenib free base(GSK2118436A) GSK2118436A Dabrafenib (GSK2118436A) Dabrafenib KB-57246 Debrafenib API BenzenesulfonaMide, N-[3-[5-(2-aMino-4-pyriMidinyl)-2-(1,1-diMethylethyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluoro- N-(3-(5-(2-aminopyrimidin-4-yl)-2-tert-butylthiazol-4-yl)-2-fluorophenyl)-2,6-difluorobenzenesulfonamide
• CAS:1195765-45-7
• MF:C23H20F3N5O2S2
• MW:519.56
• EINECS:689-166-9
• Mol File:1195765-45-7.mol
• 

N-[3-[5-(2-Amino-4-pyrimidinyl)-2-(tert-butyl)-4-thiazolyl]-2-fluorophenyl]-2,6-difluorobenzenesulfonamide is well known as dabrafenib. It is a drug for the treatment of cancers associated with a mutated version of the gene BRAF. Dabrafenib acts as an inhibitor of the associated enzyme B-Raf, which plays a role in the regulation of cell growth. Dabrafenib has clinical activity with a manageable safety profile in clinical trials of phase-I and -II in patients with BRAF(V600)-mutated metastatic melanoma^1,2. Its mechanism of action is acted as a Protein Kinase Inhibitor, and Cytochrome P450 3A4 Inducer, and Cytochrome P450 2B6 Inducer, and Cytochrome P450 2C8 Inducer, and Cytochrome P450 2C9 Inducer, and Cytochrome P450 2C19 Inducer, and Organic Anion Transporting Polypeptide 1B1 Inhibitor, and Organic Anion Transporting Polypeptide 1B3 Inhibitor, and Organic Anion Transporter 1 Inhibitor, and Organic Anion Transporter 3 Inhibitor, and Breast Cancer Resistance Protein Inhibitor^3,4. It is not indicated for the treatment of patients with wild-type BRAF melanoma or wild-type BRAF NSCLC. MEKINIST is not indicated for the treatment of patients with melanoma who have progressed on prior BRAF-inhibitor therapy⁵.

• Dabrafenib free base
• 
• US $0.00 /kg
• CAS:1195765-45-7
• Min. Order: 0.1kg
• Purity: 99.9%
• Supply Ability: 40-50kgs
• 2024-09-23

• Dabrafenib
• 
• US $70.00-700.00/kg
• CAS:1195765-45-7
• Min. Order: 10kg
• Purity: 0.99
• Supply Ability: 20tons
• 2024-08-27

• Company Name:Changzhou Yongfeng Biomedicine Co. Ltd.
• Tel: 15006117673
• Products Intro:Product Name:Dabrafenib,GSK2118436
  CAS:1195765-45-7
  Purity:98 Package:1g 10g 100g 1kg More...
• CB Index:58
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• Company Name:Changzhou Borl Biotechnology Co.,LTD
• Tel: 13606124132;13656121842
• Products Intro:Product Name:Dabrafenib
  CAS:1195765-45-7
  Purity:>99.0% Package:100g
• CB Index:58
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• Company Name:Shandong Chenxi Pharmaceutical Co., Ltd.
• Tel:+86-0531-88803416 13153166250
• Products Intro:Product Name:Dabrafenib
  CAS:1195765-45-7
  Purity:99.0% Package:1KG/RMB 40000
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• Company Name:Shanghai Hope Chem Co., Ltd.，
• Tel:+21-18501659228 18501659228
• Products Intro:Product Name:Dabrafenib
  CAS:1195765-45-7
  Purity:99%+HPLC Package:1KG;10KG;50KG
• CB Index:55
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• Company Name:JINAN RUIFENG PHARMACEUTICAL TECHNOLOGY CO.,LTD
• Tel:18668921571 18668921571
• Products Intro:Product Name:Dabrafenib
  CAS:1195765-45-7
  Purity:99.5% Package:1kg
• CB Index:58
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• Company Name:Shanghai Youna Biopharmaceutical Co., Ltd
• Tel: 18164002430
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• Company Name:Chunchuang (Wuhan) Technology Co., Ltd
• Tel: 15342225168
• Products Intro:Product Name:1mg;1g;10g;100g;1Kg;
  CAS:1195765-45-7
  Purity:99.5+HPLC Package:1mg;1g;10g;100g;1kg;10kg;100kg;1T
• CB Index:58
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• Company Name:Jinan XinKe Pharmaceutical Technology Co., Ltd.
• Tel:0531-88259693 17854196142
• Products Intro:Product Name:Dabrafenib base
  CAS:1195765-45-7
  Package:1kg
• CB Index:58
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