Amantadine
768-94-5 Basic informationMore
- Product Name:Amantadine
- Synonyms: 1-ADAMANTAMINE 1-Adamantanamin 1-Amantadine 1-Aminoadamatane 1-aminodiamantane 1-aminotricyclo(3.3.1.1(sup3,7))decane 1-Aminotricyclo(3.3.1.1<sup>3,7</sup>)decane 1-aminotricyclo[3.3.1.1(sup3,7)]decane
- CAS:768-94-5
- MF:C10H17N
- MW:151.25
- EINECS:212-201-2
- Mol File:768-94-5.mol
USE
Amantadine has been used for years as a treatment for Parkinson disease. The adamantanamines have twomechanisms in common:they inhibit an early step in viralreplication, most likely viral uncoating,and in somestrains, they affect a later step that probably involves viral assembly,possibly by interfering with hemagglutinin processing.The main biochemical locus of action is the influenzatype A virus M2 protein, which is an integral membrane proteinthat functions as an ion channel. The M2 channel is a protontransport system. By interfering with the function of theM2 protein, the adamantanamines inhibit acid-mediated dissociationof the ribonucleoprotein complex early in replication.They also interfere with transmembrane proton pumping,maintaining a high intracellular proton concentrationrelative to the extracellular concentration and enhancingacidic pH-induced conformational changes in the hemagglutininduring its intracellular transport at a later stage. The conformationalchanges in hemagglutinin prevent transfer of thenascent virus particles to the cell membrane for exocytosis.
Lastest Price from Amantadine manufacturers
- Amantadine
- US $980.00-750.00/kg
- CAS:768-94-5
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 5000
- 2024-12-20
- Amantadine
- US $0.00 /Kg/Drum
- CAS:768-94-5
- Min. Order: 1KG
- Purity: 98%min
- Supply Ability: 1000kg
- 2024-12-13
Browse by Nationality 768-94-5 Suppliers >Global suppliers
Beijing (15) Shanghai (94) Tianjin (4) Chongqing (4) Sichuan (13) Guangdong (25) Zhejiang (24) Fujian (6) Hunan (3) Hubei (65) Shandong (15) Shanxi (1) Henan (14) Hebei (14) Liaoning (5) Anhui (6) Jiangsu (33) Jiangxi (2) Shaanxi (4) Ningxia (1) Hong Kong (4) Other (3) Member (347) All (355)
Please select the suppliers
Recommend You Select Member Companies
Recommend You Select Member Companies
- Company Name:Sichuan Zhongbang Pharma CO.,LTD
- Tel:0830-0830-2585019 13679670161
- Products Intro:Product Name:1-AdaMantanaMine
CAS:768-94-5
Purity:98.5% Remarks:A004 More... - CB Index:69
- Related Information:Catalog(105)
- Company Name:Wuxi Helen Biotechnology Co., Ltd.,
- Tel:0510-85629785 18013409632
- Products Intro:Product Name:Amantadine
CAS:768-94-5
Purity:>=95% Package:10mg;25mg;50mg;100mg;200mg;500mg Remarks:100g - CB Index:58
- Related Information:Catalog(14081)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:1-AdaMantanaMine
CAS:768-94-5
Purity:98.0%(GC&T) Package:5G More... - CB Index:76
- Related Information:Catalog(96815)
- Company Name:Meryer (Shanghai) Chemical Technology Co., Ltd.
- Tel:021-61259108 18621169109
- Products Intro:Product Name:1-AdaMantylaMine
CAS:768-94-5
Purity:98.5% Package:5g;100g Remarks:H82005 More... - CB Index:62
- Related Information:Catalog(40228)
- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:AMantadine
CAS:768-94-5
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
- Related Information:Catalog(15839)
- Company Name:future industrial shanghai co., ltd
- Tel:400-0066400 13621662912
- Products Intro:Product Name:Adamantan-1-amine
CAS:768-94-5
Purity:98.0%(GC) Package:809RMB/ 25g More... - CB Index:65
- Related Information:Catalog(1995)