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Sugammadex sodium

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343306-79-6 Basic informationMore
USE
To facilitate tracheal intubation, mechanical ventilation, and surgical access, NMB agents are frequently used as non-anesthetic adjuncts in surgical procedures. Sugammadex is able to function as a pharmacologic sink of rocuronium and vecuronium, another non-depolarizing neuromuscular blocker, without the cardiovascular adverse effects experienced with reversal agents that directly interact with the cholinergic system. The γ-cyclodextrin has been designed to enhance binding of the guest by incorporating acidic side chains to promote an electrostatic interaction with the positive nitrogen of the blocker. Starting with γ-cyclodextrin, these side chains are readily installed by first halogenating with iodine or bromine to provide a handle for nucleophilic displacement with either 3-mercaptopropionic acid in the presence of sodium hydride or with 3-mercaptopropionic acid methyl ester and cesium carbonate. The latter requires hydrolysis with sodium hydroxide to generate sugammadex sodium.
Lastest Price from Sugammadex sodium manufacturers
  • Sugammadex Sodium
  • US $50.00 /kg
  • CAS:343306-79-6
  • Min. Order: 1kg
  • Purity: 99
  • Supply Ability: 5000
  • 2024-12-20

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  • Company Name:Beijing Sai Siyuan Biomedical Technology Co., Ltd.
  • Tel:010-87925700 13522399152
  • Products Intro:Product Name:Sugammadex
    CAS:343306-79-6
    Purity:99.5% Package:5KG
  • CB Index:58
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  • Company Name:Shanghai Rechem science Co., Ltd.
  • Tel:21-31433387 15618786686
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    Purity:98%+HPLC Package:1g;10g;100g More...
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  • Company Name:Guangzhou Dreampharm Biotechnology Co., Ltd.
  • Tel:020-36607679 17825480238
  • Products Intro:Product Name:Sugammadex sodium
    Purity:98% HPLC Package:25mg,50mg,100mg
  • CB Index:12
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  • Company Name:Suzhou Gopon Pharmaceutical Co., Ltd
  • Tel: 13358059751
  • Products Intro:CAS:343306-79-6
    Package:25kg
  • CB Index:58
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  • Company Name:Hangzhou Hua Zhe Biological Medicine Co., LTD
  • Tel:0571-5683-8096 17302275155
  • Products Intro:Product Name:Sugammadex sodium
    CAS:343306-79-6
    Purity:98%HPLC Package:5KG;1KG
  • CB Index:58
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  • Company Name:BrightGene Bio-medical Technology Co., Ltd.
  • Tel:0512-0512-62551764 18013103761
  • Products Intro:Product Name:Sugammadex Sodium
    CAS:343306-79-6
    Purity:99% HPLC Package:1Kg;5Kg;1Kg Remarks:kg More...
  • CB Index:70
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  • Company Name:YICHANG TIANRUI BIOPHARM CO., LTD
  • Tel: 18671799682
  • Products Intro:Product Name:Sugammadex Sodium
    CAS:343306-79-6
    Purity:99% HPLC Package:1kg
  • CB Index:58
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