Sugammadex sodium
343306-79-6 Basic informationMore
- Product Name:Sugammadex sodium
- Synonyms: ORG-25969/SugaMMadex Sugammadex IMP US-DMF No.: 033904 ASMF filed 6A,6B,6C,6D,6E,6F,6G,6H-Octakis-S-(2-carboxyethyl)-6A,6B,6C,... Sugammadex sodium (Org-25969) 6 Sugammadex Sodium Glucose-sodium Sulgeng glucose sodium
- CAS:343306-79-6
- MF:C72H104Na8O48S8
- MW:2177.97
- EINECS:200-838-9
- Mol File:343306-79-6.mol
-
USE
To facilitate tracheal intubation, mechanical ventilation, and surgical
access, NMB agents are frequently used as non-anesthetic adjuncts in
surgical procedures.
Sugammadex is able to function as a pharmacologic sink of rocuronium and vecuronium, another non-depolarizing
neuromuscular blocker, without the cardiovascular adverse effects
experienced with reversal agents that directly interact with the
cholinergic system. The γ-cyclodextrin has been designed to enhance
binding of the guest by incorporating acidic side chains to promote an
electrostatic interaction with the positive nitrogen of the blocker. Starting
with γ-cyclodextrin, these side chains are readily installed by first
halogenating with iodine or bromine to provide a handle for nucleophilic
displacement with either 3-mercaptopropionic acid in the presence of
sodium hydride or with 3-mercaptopropionic acid methyl ester
and cesium carbonate. The latter requires hydrolysis with sodium
hydroxide to generate sugammadex sodium.
Lastest Price from Sugammadex sodium manufacturers
- Sugammadex sodium
-
- US $0.00-0.00/KG
- CAS:343306-79-6
- Min. Order: 5KG
- Purity: 0.99
- Supply Ability: 50MT/month
- 2024-04-22
- Sugammadex sodium
-
- US $0.00 /KG
- CAS:343306-79-6
- Min. Order: 2KG
- Purity: 99% up, High Density
- Supply Ability: 20 tons
- 2024-04-22
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- Company Name:Beijing Sai Siyuan Biomedical Technology Co., Ltd.
- Tel:010-87925700 13522399152
- Products Intro:Product Name:Sugammadex
CAS:343306-79-6
Purity:99.5% Package:5KG - CB Index:58
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CAS:343306-79-6
Purity:98%+HPLC Package:1g;10g;100g More... - CB Index:58
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- Products Intro:Product Name:Sugammadex sodium Impurity
CAS:343306-79-6
Purity:95%+hplc Package:5mg/RMB 1500;15mg25mg More... - CB Index:58
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- Company Name:Guangzhou Dreampharm Biotechnology Co., Ltd.
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Purity:98% HPLC Package:25mg，50mg，100mg - CB Index:12
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- Company Name:Hangzhou Hua Zhe Biological Medicine Co., LTD
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CAS:343306-79-6
Purity:98%HPLC Package:5KG;1KG - CB Index:58
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- Products Intro:Product Name:Sugammadex Sodium
CAS:343306-79-6
Purity:99% HPLC Package:1Kg;5Kg;1Kg Remarks:kg More... - CB Index:70
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- Company Name:Nantong Xiaochang Pharmaceutical Trading Co., Ltd.
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- Products Intro:Product Name:Sugammadex sodium
CAS:343306-79-6
Purity:98%+ Package:1kg;5kg;25kg - CB Index:58
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