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Methyl (triphenylphosphoranylidene)acetate

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<ol> <li>(Methoxycarbonylmethylene)triphenylphosphorane is used in olefination reactions. Wittig reagent for the two-carbon homologation of aldehydes to &alpha;,&beta;-unsaturated esters. it undergoes the Wittig reaction with aldehydes to give substituted methyl acrylates.</li> <li>used in an efficient synthesis of pyrazoles via reaction with methyl diazoacetate in the presence of triethylamine.</li> <li>It is used in the preparation of (triphenylphosphoranylidene)-ketene.</li> <li>The Wittig reaction we performed in class involved the reaction of 2-nitrobenzaldehyde (1) with methyl (triphenylphosphoranylidene) acetate (2) to produce methyl (2E)-3-(2-nitrophenyl) acrylate (3) with a triphenylphosphine oxide (4) side product, and took place in a silica gel matrix to ensure even product dispersion for chromatography.<br /> <img alt="Wittig Reaction" id="ProductImg" src="http://www.chemicalbook.com/NewsImg/2018-01-04/2018141439819910.jpg" /></li> </ol>
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