TALIPEXOLE
101626-70-4 Basic informationMore
- Product Name:TALIPEXOLE
- Synonyms: TALIPEXOLE 5，6，7，8-Tetrahydro-6-(2-propenyl)-4H-thiazolo[4，5-d]azepin-2-amine Domin 6-Allyl-2-amino-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepine 6-Allyl-5,6,7,8-tetrahydro-4H-thiazolo[4,5-d]azepin-2-amine Talipexol Talipexol [spanish] Talipexolum
- CAS:101626-70-4
- MF:C10H15N3S
- MW:209.31
- EINECS:
- Mol File:101626-70-4.mol
-
USE
Domin was launched in Japan for Parkinson's disease. The compound is
readily accessible in two steps from I-allylhexahydro-4H-azepin4-one. Its
antiparkinson activity resides in the fact that talipexole is a selective agonist for
presynaptic dopamine D<sub>2</sub> receptors with no D<sub>1</sub> receptor activity. It is a clonidine-like α<sub>2</sub>-adrenoreptor agonist and has fewer GI side effects than bromocriptine the most
widely used dopamine angonist. Also it is 70 times more potent than bromocriptine
and has a more rapid onset of action. In addition to its anti-tremor activity there was
a sedative effect but no emesis. The latter probably a result of talipexole's 5-HT<sub>3</sub>
receptor antagonistic activity. Its metabolites have no biological activity, there was
no development of tolerence and its effect could be enhanced by L-dopa.
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- Company Name:Tianjin Kailiqi Biotechnology Co., Ltd.
- Tel: 15076683720
- Products Intro:Product Name:Talipexole
CAS:101626-70-4
Purity:≥98% Package:1g,5g,10g,25g根据客户需要分装 Remarks:Not For Human Use, Lab Use Only. - CB Index:55
- Related Information:Catalog(4602)
- Company Name:Beijing Solarbio Science & Tecnology Co., Ltd.
- Tel:010-50973130 4009686088
- Products Intro:CAS:101626-70-4
- CB Index:68
- Related Information:Catalog(29785)
- Company Name:Amadis Chemical Company Limited
- Tel:571-89925085
- Products Intro:Product Name:Talipexole
CAS:101626-70-4
Purity:0.97 Package:mgs,gs,kgs Remarks:A908444 - CB Index:58
- Related Information:Catalog(131957)
- Company Name:Shaanxi Dideu Medichem Co. Ltd
- Tel:+86-029-89586680 +86-18192503167
- Products Intro:Product Name:TALIPEXOLE USP/EP/BP
CAS:101626-70-4
Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer - CB Index:58
- Related Information:Catalog(7724)
- Company Name:Beijing Jin Ming Biotechnology Co., Ltd.
- Tel:010-60605840 15801484223;
- Products Intro:Product Name:Talipexole
CAS:101626-70-4
Package:1mg Remarks: 试剂级 - CB Index:58
- Related Information:Catalog(29774)