ecallantide

• Product Name:ecallantide
• Synonyms: ecallantide DX 88 ecallantide USP/EP/BP Cys16-Cys40 Cys32-Cys53) H-Glu-Ala-Met-His-Ser-Phe-Cys-Ala-Phe-Lys-Ala-Asp-Asp-Gly-Pro-Cys-Arg-Ala-Ala-His-Pro-Arg-Trp-Phe-Phe-Asn-Ile-Phe-Thr-Arg-Gln-Cys-Glu-Glu-Phe-Ile-Tyr-Gly-Gly-Cys-Glu-Gly-Asn-Gln-Asn-Arg-Phe-Glu-Ser-Leu-Glu-Glu-Cys-Lys-Lys-Met-Cys-Thr-Arg-Asp-OH(Disulfide bridge：Cys7-Cys57
• CAS:460738-38-9
• MF:C305H442N88O91S8
• MW:7053.82798
• EINECS:
• Mol File:460738-38-9.mol
• 

Ecallantide, also known as DX-88, was approved in 2009 in the United States for treatment of hereditary angioedema (HAE), a condition characterized by episodic attacks of localized edema in cutaneous and mucosal tissues. HAE results from deficiencies or disorders of C1-esterase inhibitor protein (C1- 1NH). Mutation of the gene that encodes C1-1NH causes the lack or altered activity of the serine protease, C1-1NH. C1-1NH regulates the kallikrein–kinin (contact activation) and complement cascade systems. Ecallantide (DX-88) was designed to inhibit the action of plasma kallikrein. Ecallantide is a potent and selective inhibitor of plasma kallikrein with a Ki= 25 pM. The discovery program that identified ecallantide used phage display technology and a library of designed variants of the first Kunitz domain of TFPI. Ecallantide, a 60-amino acid peptide, with 3-disulfide bonds, differs from TFPI by 7-amino acids. Ecallantide has been developed as a subcutaneous administered formulation.

• Ecallantide
• 
• US $0.00 /g
• CAS:460738-38-9
• Min. Order: 1g
• Purity: 98%min
• Supply Ability: 1000g
• 2024-07-19

• Company Name:Chengdu Youngshe Chemical Co., Ltd.
• Tel:+86-17380623303 +86-17380623303
• Products Intro:Product Name:Ecallantide
  CAS:460738-38-9
  Purity:95% Package:1G; 10G; 100G
• CB Index:58
• Related Information:Catalog(5749)

• Company Name:Hangzhou Peptidego Biotech Co.,Ltd.
• Tel:0571-87213919
• Products Intro:Product Name:ecallantide
  CAS:460738-38-9
  Purity:95% or 98% HPLC Package:1mg；5mg；10mg；50mg；100mg,1g or according to customer's detail requirement.
• CB Index:58
• Related Information:Catalog(6526)

• Company Name:Henan Alfa Chemical Co., Ltd
• Tel: +8618339805032
• Products Intro:CAS:460738-38-9
  Purity:97%+ Package:25g; 100g; 500g; 1kg; 25kg;bulk package
• CB Index:58
• Related Information:Catalog(13141)

• Company Name:Wuhan Fortuna Chemical Co., Ltd
• Tel:+86-027-59207850
• Products Intro:Product Name:Ecallantide
  CAS:460738-38-9
  Purity:98%min Package:1g
• CB Index:58
• Related Information:Catalog(5964)

• Company Name:Dideu Industries Group Limited
• Tel:+86-29-89586680 +86-15129568250
• Products Intro:Product Name:ecallantide
  CAS:460738-38-9
  Purity:99.9% Package:25kgs/Drum;200kgs/Drum Remarks:FDA GMP CEP Approved Manufacturer
• CB Index:58
• Related Information:Catalog(25961)

• Company Name:Wuxi Helen Biotechnology Co., Ltd.,
• Tel:0510-85629785 18013409632
• Products Intro:Product Name:ecallantide
  CAS:460738-38-9
  Purity:95%+ Package:根据客户需求包装
• CB Index:58
• Related Information:Catalog(14092)