IKARUGAMYCIN
36531-78-9 Basic informationMore
- Product Name:IKARUGAMYCIN
- Synonyms: TU-6239 C3 IKARUGAMYCIN 14,17-Metheno-17H-as-indaceno[3,2-k][1,6]diazacycloheptadecine-9,16,18(1H)-trione 3-Ethyl-2,3,3a,5a,5b,6,10,11,12,13,14,15,20a,21,21a,21b-hexadecahydro-22-hydroxy-2-methyl-, (2R,3R,3aS,5aR,5bS,7Z,14S,19E,20aS,21aR,21bR)- 14,17-Metheno-17H-as-indaceno[3,2-k][1,6]diazacycloheptadecine-9,16,18(1H)-trione, 3-ethyl-2,3,3a,5a,5b,6,10,11,12,13,14,15,20a,21,21a,21b-hexadecahydro-22-hydroxy-2-methyl-, (2R,3R,3aS,5aR,5bS,7Z,14S,19E,20aS,21aR,21bR)- WSUGGLXIPUHOSG-XSYQVIBFSA-N turbinomycin
- CAS:36531-78-9
- MF:C29H38N2O4
- MW:478.62
- EINECS:
- Mol File:36531-78-9.mol
-
USE
Ikarugamycin is an unusual pentacyclic tetramic acid produced by Streptomyces phaeochromogenes, with potent activity against the protozoan, Trichomonas vaginalis, reported in 1972. Ikarugamycin also demonstrates selective Gram positive antibacterial activity, and anti-ulcer activity possibly via inhibition of H. pylori. In addition, ikarugamycin inhibits the uptake of oxidized low-density lipoprotein in mouse macrophages, blocks PMA and Nef-mediated cell surface CD4 down-regulation, and inhibits clathrin-coated pit-mediated endocytosis. Importantly, ikarugamycin is emerging as a useful agent for studying the process of endocytosis.
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- Company Name:Guangzhou Isun Pharmaceutical Co., Ltd
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- Products Intro:Product Name:IkarugaMycin
CAS:36531-78-9
Purity:98% (HPLC) Package:25Mg; 1g; 100g; 500g More... - CB Index:55
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- Company Name:Sigma-Aldrich
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CAS:36531-78-9
Purity:>=98% (HPLC) Package:500μg Remarks:SML0188 More... - CB Index:80
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CAS:36531-78-9
Purity:99% Package:500μg;2.5mg More... - CB Index:58
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CAS:36531-78-9
Purity:>99% by HPLC Package:1mg;5mg More... - CB Index:58
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CAS:36531-78-9
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- Company Name:ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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CAS:36531-78-9
Purity:98% Package:10 mg;50 mg;100 mg;500 mg;1 g;5 g;10 g - CB Index:58
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