KANAMYCIN
59-01-8 Basic informationMore
- Product Name:KANAMYCIN
- Synonyms: y-alpha-d-glucopyranosyl-(1-4))-2-deoxy- Kannamycin Monosulfate KANAMYCIN BASE ENTERPRISE STANDARD 1-O-[(1R)-2α-Hydroxy-3β-(3-amino-3-deoxy-α-D-glucopyranosyloxy)-4α,6α-diaminocyclohexane-1β-yl]-6-amino-6-deoxy-α-D-glucopyranose 4-O-(6-Amino-6-deoxy-α-D-glucopyranosyl)-6-O-(3-amino-3-deoxy-α-D-glucopyranosyl)-2-deoxy-D-streptamine (2R,3S,4S,5R,6R)-2-(aminomethyl)-6-[(1R,2R,3S,4R,6S)-4,6-diamino-3-[(2S,3R,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methylol-tetrahydropyran-2-yl]oxy-2-hydroxy-cyclohexoxy]tetrahydropyran-3,4,5-triol KANAMYCIN BASE 4))-2-deoxy-y-alpha-d-glucopyranosyl-(
- CAS:59-01-8
- MF:C18H36N4O11
- MW:484.5
- EINECS:200-411-7
- Mol File:59-01-8.mol
USE
Kanamycin is a well-known bactericidal antibiotic. It belongs to the aminoglycoside antibiotic group. It can be used for the treatment of various pathogens including E. coli, Proteus species (both indole-positive and indole-negative), Enterobacter aerogenes, Klebsiella pneumoniae, Serratia marcescens and Acinetobacter species<sup>1-4</sup>. Kanamycin is isolated from the bacterium Streptomyces kanamyceticus and its most commonly used form is kanamycin sulfate5. Aminoglycoside-type drug take actions through “irreversibly” binding to the 30S subunit of the ribosome, further blocking the protein synthesis. Kanamycin kills bacteria cells binds to four nucleotides of 16S rRNA and a single amino acid of protein S12. This interferes with decoding site in the vicinity of nucleotide 1400 in 16S rRNA of 30S subunit. This region interacts with the wobble base in the anticodon of tRNA. This leads to interference with the initiation complex, misreading of mRNA so incorrect amino acids are inserted into the polypeptide leading to nonfunctional or toxic peptides and the breakup of polysomes into nonfunctional monosomes<sup>5</sup>.
Lastest Price from KANAMYCIN manufacturers
- KANAMYCIN
- US $0.00 /bou
- CAS:59-01-8
- Min. Order: 15bou
- Purity: >765/mg
- Supply Ability: 15000bou
- 2025-01-02
- Kanamycin
- US $1.00 /kg
- CAS:59-01-8
- Min. Order: 1kg
- Purity: 99%
- Supply Ability: 10 mt
- 2024-11-05
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- Company Name:Hubei kangen Pharmaceutical Chemical Co., Ltd
- Tel:15337215803 15337215803
- Products Intro:Product Name:KANAMYCIN
CAS:59-01-8
Purity:99% More... - CB Index:56
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- Company Name:Jinan Wald Chemical Co., Ltd.
- Tel:0531-88773586 13210588999
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CAS:59-01-8
- CB Index:58
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- Company Name:TargetMol Chemicals Inc.
- Tel:021-021-33632979 15002134094
- Products Intro:Product Name:Kanamycin A
CAS:59-01-8
Package:5mg/RMB 148;10mg/RMB 220;25mg/RMB 375 - CB Index:58
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- Company Name:Wuhan DKY Technology Co.,Ltd.
- Tel:27-81302488 18007166089
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Purity:99 Package:1kg,5kg,25kg More... - CB Index:58
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- Products Intro:Product Name:Amikacin EP Impurity D; Kanamycin A
CAS:59-01-8
Purity:95% HPLC Package:10mg;25mg;50mg;100mg - CB Index:56
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- Company Name:Finetech Industry Limited
- Tel:027-87465837 19945049750
- Products Intro:Product Name:KANAMYCIN
CAS:59-01-8
Purity:98% Package:1g;10g;25g;500g;1kg - CB Index:58
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