9-CIS-RETINOIC ACID
5300-03-8 Basic informationMore
- Product Name:9-CIS-RETINOIC ACID
- Synonyms: RETINOIC ACID, 9-CIS- RARECHEM AL BE 0738 (2E,4E,6Z,8E)-3,7-DIMETHYL-9-(2,6,6-TRIMETHYLCYCLOHEX-1-ENYL)NONA-2,4,6,8-TETRAENOIC ACID 9-CIS-RETINOIC ACID 9-CIS-TRETINOIN 9-cis-tretinoi 3,7-dimethyl-9-(2,6,6-trimethyl-1-cyclohexenyl)nona-2,4,6,8-t ALIRETINOIN
- CAS:5300-03-8
- MF:C20H28O2
- MW:300.44
- EINECS:1533716-785-6
- Mol File:5300-03-8.mol
-
USE
Alitretinoin was introduced in the US for the topical treatment of
cutaneous lesions in patients with Kaposi's sarcoma (KS), the most frequent
malignancy observed in AIDS patients. It is a derivative of 9-cis-retinoic acid (9-
cis-RA) identified as an endogenous hormone in mammalian tissues. Alitretinoin
binds to all isoforms of the intracellular retinoid X (RXR) and retinoid A (RAR)
receptors thus inducing cell differentiation, increasing cell apoptosis and
inhibiting cellular proliferation in experimental models of human cancer. In an
international phase III trial in patients with KS, 42% of 82 patients treated with
0.1% gel formulation experienced complete or partial responses cf 7% for
controls. Alitretinoin is the first topical therapy for KS and is expected to be a
new option to its traditional management.
Lastest Price from 9-CIS-RETINOIC ACID manufacturers
- 9-cis-Retinoic Acid
-
- US $0.00 /KG
- CAS:5300-03-8
- Min. Order: 1KG
- Purity: 99%
- Supply Ability: 50000KG/month
- 2023-10-16
- 9-cis-Retinoic Acid
-
- US $30.00-10.00/KG
- CAS:5300-03-8
- Min. Order: 50KG
- Purity: 99%
- Supply Ability: 500000kg
- 2023-09-11
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- Company Name:Hubei wei shi reagent group ltd., company
- Tel:027-027-59102966 18717199209
- Products Intro:Product Name:9-cis-RetinoicAcid
CAS:5300-03-8
Purity:99% Package:10g/RMB 11500 - CB Index:58
- Related Information:Catalog(5764)
- Company Name:J & K SCIENTIFIC LTD.
- Tel:010-82848833 400-666-7788
- Products Intro:Product Name:9-cis-Retinoic Acid
CAS:5300-03-8
Package:50Mg,5Mg More... - CB Index:76
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- Company Name:Chemvon Biotechnology Co., Ltd
- Tel:021-50790412
- Products Intro:Product Name:9-cis-Retinoic Acid
CAS:5300-03-8
Purity:98% Package:1g, 10g, 100g, 200g, 1kg, 5kg More... - CB Index:57
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- Company Name:3B Pharmachem (Wuhan) International Co.,Ltd.
- Tel:821-50328103-801 18930552037
- Products Intro:Product Name:9-CIS-RETINOIC ACID
CAS:5300-03-8
Purity:99% HPLC Package:1Mg ; 5Mg;10Mg ;100Mg;250Mg ;500Mg ;1g;2.5g ;5g ;10g More... - CB Index:69
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- Company Name:Nanjing Chemlin Chemical Co., Ltd
- Tel:025-83697070
- Products Intro:Product Name:9-cis-Retinoic acid
CAS:5300-03-8
Purity:98% Package:5KG;1KG More... - CB Index:64
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- Company Name:Shandong Xiya Chemical Co., Ltd
- Tel:13355009207 13355009207
- Products Intro:CAS:5300-03-8
Purity:>=98.0% (HPLC) Package:1mg;5mg - CB Index:57
- Related Information:Catalog(18739)